Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
H3C0T1_TETNGProtein kinase domain-containing protein. (283 aa)    
Predicted Functional Partners:
H3CXQ0_TETNG
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.
    
 0.655
DCAF7
DDB1 and CUL4 associated factor 7.
   
 
 0.547
Q4SV04_TETNG
Chromosome undetermined SCAF13832, whole genome shotgun sequence; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.526
H3C119_TETNG
Methyl CpG binding protein 2.
    
 0.472
H3CL95_TETNG
E1A binding protein p300 b.
   
  0.450
H3D5Y4_TETNG
E1A binding protein p300 a.
   
  0.450
H3CIB9_TETNG
Daxx domain-containing protein.
    
 
 0.427
H3DLF3_TETNG
Death-domain associated protein.
    
 
 0.427
SUMO1-2
Small ubiquitin-related modifier.
    
 0.415
SUMO1
Small ubiquitin like modifier 1.
    
 0.415
Your Current Organism:
Tetraodon nigroviridis
NCBI taxonomy Id: 99883
Other names: T. nigroviridis, spotted green pufferfish
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