Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
H3C0U9_TETNGLysine (K)-specific demethylase 4C. (1067 aa)    
Predicted Functional Partners:
KDM1B
Lysine demethylase 1B.
   
 0.687
H3C9P4_TETNG
Amino_oxidase domain-containing protein.
   
 0.609
H3DIP9_TETNG
Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.
   
 0.609
H3C1U0_TETNG
RING-type domain-containing protein.
    
 0.546
H3CE84_TETNG
Tumor protein p53 binding protein, 1.
     
 0.530
Q4RGY9_TETNG
Chromosome undetermined SCAF15083, whole genome shotgun sequence.
     
  0.530
H3DLI5_TETNG
RAD50 homolog, double strand break repair protein.
     
  0.522
H3D2P2_TETNG
Androgen receptor.
    
 0.501
H3DEC1_TETNG
Uncharacterized protein.
    
 0.501
H3CC54_TETNG
Protein inhibitor of activated STAT, 4a.
   
 0.491
Your Current Organism:
Tetraodon nigroviridis
NCBI taxonomy Id: 99883
Other names: T. nigroviridis, spotted green pufferfish
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