Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
H3C102_TETNGIntersectin 1 (SH3 domain protein). (1664 aa)    
Predicted Functional Partners:
H3D0I8_TETNG
AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]
    
 0.975
H3CQN8_TETNG
AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.
   
 0.965
H3DL95_TETNG
FCH domain only 1.
   
 0.953
H3C550_TETNG
Synaptojanin 1.
   
 
 0.948
Q4SAX7_TETNG
Chromosome 3 SCAF14679, whole genome shotgun sequence.
   
 0.935
H3D1T6_TETNG
Uncharacterized protein.
   
 0.935
H3CFP1_TETNG
NECAP endocytosis associated 1.
    
 0.933
H3CRQ8_TETNG
DUF1681 domain-containing protein.
    
 0.933
H3DAZ7_TETNG
NECAP endocytosis associated 2.
    
 0.933
H3CM05_TETNG
Adaptor related protein complex 4 subunit beta 1.
    
 0.932
Your Current Organism:
Tetraodon nigroviridis
NCBI taxonomy Id: 99883
Other names: T. nigroviridis, spotted green pufferfish
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