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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
H3C102_TETNGIntersectin 1 (SH3 domain protein). (1664 aa)    
Predicted Functional Partners:
H3D0I8_TETNG
AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]
    
 0.991
H3CQN8_TETNG
AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.
   
 0.990
H3CM05_TETNG
Adaptor related protein complex 4 subunit beta 1.
    
 0.989
H3CQC6_TETNG
AP complex subunit beta.
    
 0.989
H3DEJ4_TETNG
AP complex subunit beta.
    
 0.989
Q4SAX7_TETNG
Chromosome 3 SCAF14679, whole genome shotgun sequence.
   
 0.970
H3D1T6_TETNG
Uncharacterized protein.
   
 0.970
H3DGQ9_TETNG
Stonin-1; May be involved in the endocytic machinery.
   
 0.970
H3CFP1_TETNG
NECAP endocytosis associated 1.
    
 0.967
H3CRQ8_TETNG
DUF1681 domain-containing protein.
    
 0.967
Your Current Organism:
Tetraodon nigroviridis
NCBI taxonomy Id: 99883
Other names: T. nigroviridis, spotted green pufferfish
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