Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
H3C116_TETNGRetinol dehydrogenase 8a; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (320 aa)    
Predicted Functional Partners:
H3DR17_TETNG
Hydroxysteroid (17-beta) dehydrogenase 2; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
 
 0.616
Q4T1F0_TETNG
Chromosome 12 SCAF10644, whole genome shotgun sequence; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
 0.594
H3CRK8_TETNG
Cytochrome P450, family 11, subfamily C, polypeptide 1; Belongs to the cytochrome P450 family.
   
 
 0.497
H3CSL9_TETNG
Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]
   
 
 0.497
MLKL
Mixed lineage kinase domain like pseudokinase.
    
 0.494
H3CEJ1_TETNG
Steroidogenic acute regulatory protein, mitochondrial; Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone.
      
 0.462
Q4S9I3_TETNG
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
  
 0.455
H3D371_TETNG
Taste receptor, type 1, member 1.
      
 0.443
H3CPR8_TETNG
Zgc:65997; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
 
 0.442
H3CVV9_TETNG
Cytochrome P450, family 19, subfamily A, polypeptide 1a; Belongs to the cytochrome P450 family.
   
 
 0.442
Your Current Organism:
Tetraodon nigroviridis
NCBI taxonomy Id: 99883
Other names: T. nigroviridis, spotted green pufferfish
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