Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
H3C1Q5_TETNGApoptosis, caspase activation inhibitor. (304 aa)    
Predicted Functional Partners:
H3CHL3_TETNG
Focadhesin.
    
 
 0.962
H3D0A2_TETNG
Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.
    
 0.846
H3D019_TETNG
Caspase 9, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.
     
 0.612
H3BZT2_TETNG
Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
     
 0.588
H3C3H0_TETNG
Noggin; Belongs to the noggin family.
      
 0.588
cyc
Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain (By similarity).
     
 0.588
H3CGT9_TETNG
Protein phosphatase 4, regulatory subunit 4.
      
 0.566
BPHL
Biphenyl hydrolase like.
      
 0.566
Q4RHA7_TETNG
Chromosome 3 SCAF15050, whole genome shotgun sequence.
      
 0.566
Q4SW32_TETNG
Chromosome undetermined SCAF13692, whole genome shotgun sequence.
    
 
 0.556
Your Current Organism:
Tetraodon nigroviridis
NCBI taxonomy Id: 99883
Other names: T. nigroviridis, spotted green pufferfish
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