Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
H3CAI9_TETNGSerpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1; Belongs to the serpin family. (363 aa)    
Predicted Functional Partners:
H3DEQ9_TETNG
Plasminogen activator, tissue.
  
 0.971
H3BYW3_TETNG
Vitronectin b.
   
 0.951
H3CJ30_TETNG
Vitronectin a.
   
 0.951
H3D5E2_TETNG
Angiotensin II receptor, type 1b; Belongs to the G-protein coupled receptor 1 family.
    
 0.929
H3CH29_TETNG
Peptidase S1 domain-containing protein.
  
 0.926
H3D2T3_TETNG
Uncharacterized protein.
  
 0.926
Q4RQD7_TETNG
Chromosome 17 SCAF15006, whole genome shotgun sequence; Belongs to the peptidase S1 family.
  
 0.926
H3C6P0_TETNG
Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...]
   
 0.880
H3BW12_TETNG
Uncharacterized protein.
    
 
 0.723
H3DNV0_TETNG
Transforming growth factor beta; Belongs to the TGF-beta family.
   
 
 0.709
Your Current Organism:
Tetraodon nigroviridis
NCBI taxonomy Id: 99883
Other names: T. nigroviridis, spotted green pufferfish
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