Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
H3CAS5_TETNGGlutathione peroxidase; Belongs to the glutathione peroxidase family. (189 aa)    
Predicted Functional Partners:
Q4S6V6_TETNG
Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
   
 0.980
H3DE66_TETNG
Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
  
 0.979
H3DAV4_TETNG
Glutathione peroxidase; Belongs to the glutathione peroxidase family.
  
 
 0.843
GPX2
Glutathione peroxidase; Belongs to the glutathione peroxidase family.
  
 
 0.719
H3CX53_TETNG
Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family.
   
 0.687
H3DQX1_TETNG
Peroxiredoxin 5.
   
 
 0.660
Q4SW75_TETNG
Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase.
    
 
 0.629
Q4SFM2_TETNG
Chromosome 7 SCAF14601, whole genome shotgun sequence.
   
 
 0.628
H3CJF7_TETNG
Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.
  
 
 0.617
H3DQR8_TETNG
Peroxiredoxin 3.
   
 
 0.617
Your Current Organism:
Tetraodon nigroviridis
NCBI taxonomy Id: 99883
Other names: T. nigroviridis, spotted green pufferfish
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