DENND2A protein (Tetraodon nigroviridis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

DENND2A

DENN domain containing 2A. (659 aa)

Predicted Functional Partners:

H3D153_TETNG

0.555

H3D1L6_TETNG

0.555

H3DLL3_TETNG

0.475

H3D8N4_TETNG

0.460

H3CZ97_TETNG

0.458

H3CQ88_TETNG

0.444

H3DFV8_TETNG

0.416

H3DK01_TETNG

0.416

H3CHN4_TETNG

0.410

RAB9A

0.403

Your Current Organism:

Tetraodon nigroviridis

NCBI taxonomy Id: 99883
Other names: T. nigroviridis, spotted green pufferfish

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DENND2A	H3CHN4_TETNG	ENSTNIP00000006002	ENSTNIP00000007762	DENN domain containing 2A.	ST13 Hsp70 interacting protein.	0.410
DENND2A	H3CQ88_TETNG	ENSTNIP00000006002	ENSTNIP00000010422	DENN domain containing 2A.	Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.	0.444
DENND2A	H3CZ97_TETNG	ENSTNIP00000006002	ENSTNIP00000013582	DENN domain containing 2A.	Si:dkey-6b12.5.	0.458
DENND2A	H3D153_TETNG	ENSTNIP00000006002	ENSTNIP00000014239	DENN domain containing 2A.	Si:dkey-16l2.16.	0.555
DENND2A	H3D1L6_TETNG	ENSTNIP00000006002	ENSTNIP00000014404	DENN domain containing 2A.	RAB35, member RAS oncogene family b.	0.555
DENND2A	H3D8N4_TETNG	ENSTNIP00000006002	ENSTNIP00000016875	DENN domain containing 2A.	DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family.	0.460
DENND2A	H3DFV8_TETNG	ENSTNIP00000006002	ENSTNIP00000019402	DENN domain containing 2A.	Intersectin 2a.	0.416
DENND2A	H3DK01_TETNG	ENSTNIP00000006002	ENSTNIP00000020847	DENN domain containing 2A.	Uncharacterized protein.	0.416
DENND2A	H3DLL3_TETNG	ENSTNIP00000006002	ENSTNIP00000021411	DENN domain containing 2A.	Sulfite oxidase.	0.475
DENND2A	RAB9A	ENSTNIP00000006002	ENSTNIP00000001570	DENN domain containing 2A.	RAB9A, member RAS oncogene family.	0.403
H3CHN4_TETNG	DENND2A	ENSTNIP00000007762	ENSTNIP00000006002	ST13 Hsp70 interacting protein.	DENN domain containing 2A.	0.410
H3CQ88_TETNG	DENND2A	ENSTNIP00000010422	ENSTNIP00000006002	Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.	DENN domain containing 2A.	0.444
H3CQ88_TETNG	H3D153_TETNG	ENSTNIP00000010422	ENSTNIP00000014239	Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.	Si:dkey-16l2.16.	0.606
H3CQ88_TETNG	H3D1L6_TETNG	ENSTNIP00000010422	ENSTNIP00000014404	Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.	RAB35, member RAS oncogene family b.	0.606
H3CQ88_TETNG	RAB9A	ENSTNIP00000010422	ENSTNIP00000001570	Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.	RAB9A, member RAS oncogene family.	0.715
H3CZ97_TETNG	DENND2A	ENSTNIP00000013582	ENSTNIP00000006002	Si:dkey-6b12.5.	DENN domain containing 2A.	0.458
H3CZ97_TETNG	H3DFV8_TETNG	ENSTNIP00000013582	ENSTNIP00000019402	Si:dkey-6b12.5.	Intersectin 2a.	0.813
H3CZ97_TETNG	H3DK01_TETNG	ENSTNIP00000013582	ENSTNIP00000020847	Si:dkey-6b12.5.	Uncharacterized protein.	0.813
H3CZ97_TETNG	RAB9A	ENSTNIP00000013582	ENSTNIP00000001570	Si:dkey-6b12.5.	RAB9A, member RAS oncogene family.	0.636
H3D153_TETNG	DENND2A	ENSTNIP00000014239	ENSTNIP00000006002	Si:dkey-16l2.16.	DENN domain containing 2A.	0.555