H3CDK2_TETNG protein (Tetraodon nigroviridis)

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H3CDK2_TETNG

DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. (475 aa)

Predicted Functional Partners:

H3DD39_TETNG

0.953

NTHL1

0.924

H3D5V9_TETNG

0.906

H3D5X1_TETNG

0.902

MUTYH

0.876

CUL7

0.846

UNG

0.837

H3DKM8_TETNG

0.815

H3DA19_TETNG

0.811

H3CPM0_TETNG

0.807

Your Current Organism:

Tetraodon nigroviridis

NCBI taxonomy Id: 99883
Other names: T. nigroviridis, spotted green pufferfish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CUL7	H3CDK2_TETNG	ENSTNIP00000016365	ENSTNIP00000006325	Cullin 7; Belongs to the cullin family.	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	0.846
H3CDK2_TETNG	CUL7	ENSTNIP00000006325	ENSTNIP00000016365	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	Cullin 7; Belongs to the cullin family.	0.846
H3CDK2_TETNG	H3CPM0_TETNG	ENSTNIP00000006325	ENSTNIP00000010203	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	Macrophage erythroblast attacher.	0.807
H3CDK2_TETNG	H3D5V9_TETNG	ENSTNIP00000006325	ENSTNIP00000015899	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	Excision repair cross-complementation group 4.	0.906
H3CDK2_TETNG	H3D5X1_TETNG	ENSTNIP00000006325	ENSTNIP00000015911	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	AP_endonuc_2 domain-containing protein.	0.902
H3CDK2_TETNG	H3DA19_TETNG	ENSTNIP00000006325	ENSTNIP00000017360	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	Polynucleotide kinase 3'-phosphatase.	0.811
H3CDK2_TETNG	H3DD39_TETNG	ENSTNIP00000006325	ENSTNIP00000018432	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.953
H3CDK2_TETNG	H3DKM8_TETNG	ENSTNIP00000006325	ENSTNIP00000021075	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	8-oxoguanine DNA glycosylase.	0.815
H3CDK2_TETNG	MUTYH	ENSTNIP00000006325	ENSTNIP00000013608	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	Adenine DNA glycosylase; Adenine glycosylase active on G-A mispairs.	0.876
H3CDK2_TETNG	NTHL1	ENSTNIP00000006325	ENSTNIP00000017080	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	Endonuclease III-like protein 1; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines; Belongs to the Nth/MutY family.	0.924
H3CDK2_TETNG	UNG	ENSTNIP00000006325	ENSTNIP00000018961	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.	0.837
H3CPM0_TETNG	H3CDK2_TETNG	ENSTNIP00000010203	ENSTNIP00000006325	Macrophage erythroblast attacher.	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	0.807
H3D5V9_TETNG	H3CDK2_TETNG	ENSTNIP00000015899	ENSTNIP00000006325	Excision repair cross-complementation group 4.	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	0.906
H3D5V9_TETNG	H3D5X1_TETNG	ENSTNIP00000015899	ENSTNIP00000015911	Excision repair cross-complementation group 4.	AP_endonuc_2 domain-containing protein.	0.951
H3D5V9_TETNG	H3DD39_TETNG	ENSTNIP00000015899	ENSTNIP00000018432	Excision repair cross-complementation group 4.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.951
H3D5V9_TETNG	H3DKM8_TETNG	ENSTNIP00000015899	ENSTNIP00000021075	Excision repair cross-complementation group 4.	8-oxoguanine DNA glycosylase.	0.536
H3D5V9_TETNG	NTHL1	ENSTNIP00000015899	ENSTNIP00000017080	Excision repair cross-complementation group 4.	Endonuclease III-like protein 1; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines; Belongs to the Nth/MutY family.	0.880
H3D5X1_TETNG	H3CDK2_TETNG	ENSTNIP00000015911	ENSTNIP00000006325	AP_endonuc_2 domain-containing protein.	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	0.902
H3D5X1_TETNG	H3D5V9_TETNG	ENSTNIP00000015911	ENSTNIP00000015899	AP_endonuc_2 domain-containing protein.	Excision repair cross-complementation group 4.	0.951
H3D5X1_TETNG	H3DA19_TETNG	ENSTNIP00000015911	ENSTNIP00000017360	AP_endonuc_2 domain-containing protein.	Polynucleotide kinase 3'-phosphatase.	0.793

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