STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
H3CFD3_TETNGWD repeat domain, phosphoinositide interacting 2. (133 aa)    
Predicted Functional Partners:
H3D0U0_TETNG
ATG16 autophagy related 16-like 1 (S. cerevisiae).
   
 0.980
WIPI1
WD repeat domain, phosphoinositide interacting 1.
  
  
 
0.901
H3CRQ2_TETNG
Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.
    
 0.894
H3CI61_TETNG
Autophagy protein 5; Involved in autophagic vesicle formation.
    
 0.813
Q4SX49_TETNG
Autophagy protein 5; Involved in autophagic vesicle formation.
    
 0.813
H3C6U7_TETNG
WD_REPEATS_REGION domain-containing protein.
   
 0.808
ATG16L2
ATG16 autophagy related 16-like 2 (S. cerevisiae).
   
 0.808
H3DAG1_TETNG
Autophagy-related protein 3.
    
 0.792
H3D1Y5_TETNG
Beclin 1, autophagy related.
    
 0.776
H3DBF4_TETNG
Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]
    
 0.776
Your Current Organism:
Tetraodon nigroviridis
NCBI taxonomy Id: 99883
Other names: T. nigroviridis, spotted green pufferfish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.