STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
H3CI46_TETNGPlatelet derived growth factor d; Belongs to the PDGF/VEGF growth factor family. (312 aa)    
Predicted Functional Partners:
H3D673_TETNG
Platelet derived growth factor c; Belongs to the PDGF/VEGF growth factor family.
     
0.913
H3DKT6_TETNG
Platelet-derived growth factor alpha polypeptide b; Belongs to the PDGF/VEGF growth factor family.
     
 0.712
H3DND0_TETNG
Platelet-derived growth factor alpha polypeptide a; Belongs to the PDGF/VEGF growth factor family.
     
 0.712
H3C0G2_TETNG
PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family.
     
 0.654
H3D1Q8_TETNG
PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family.
     
 0.654
H3DNC1_TETNG
Platelet-derived growth factor beta polypeptide a; Belongs to the PDGF/VEGF growth factor family.
     
 0.654
H3D9P7_TETNG
Platelet-derived growth factor receptor, beta polypeptide.
    
 
 0.653
UTS2
Urotensin 2, alpha.
      
 0.635
H3C6P0_TETNG
Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...]
     
 0.551
H3CH29_TETNG
Peptidase S1 domain-containing protein.
     
 0.492
Your Current Organism:
Tetraodon nigroviridis
NCBI taxonomy Id: 99883
Other names: T. nigroviridis, spotted green pufferfish
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.