STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
H3D4C5_TETNGVacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway. (182 aa)    
Predicted Functional Partners:
H3CHD5_TETNG
Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.
   
 0.998
Q4S0Z5_TETNG
Chromosome 5 SCAF14773, whole genome shotgun sequence.
   
 0.995
H3C5N0_TETNG
Uncharacterized protein.
   
 0.969
H3DFI0_TETNG
VPS26, retromer complex component B.
   
 0.969
H3C661_TETNG
TBC1 domain family, member 5.
    
 
 0.967
ITPA
Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family.
  
  
 0.950
SNX2
Sorting nexin 2.
   
 0.937
H3CSQ1_TETNG
Sorting nexin 1a.
   
 0.910
H3CW14_TETNG
Sorting nexin 1b.
   
 0.910
H3CYI9_TETNG
Ankyrin repeat domain 27 (VPS9 domain).
    
 
 0.908
Your Current Organism:
Tetraodon nigroviridis
NCBI taxonomy Id: 99883
Other names: T. nigroviridis, spotted green pufferfish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.