STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Q4RXA7_TETNGGuanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1. (350 aa)    
Predicted Functional Partners:
Q4S8H4_TETNG
Phosphodiesterase 6G, cGMP-specific, rod, gamma, paralog b.
   
 0.995
Q4RX95_TETNG
Guanine nucleotide binding protein (G protein), beta polypeptide 1b.
   
 0.976
H3C2G0_TETNG
Rhodopsin.
   
 0.972
rho
Rhodopsin; Photoreceptor required for image-forming vision at low light intensity. While most salt water fish species use retinal as chromophore, most freshwater fish use 3-dehydroretinal, or a mixture of retinal and 3-dehydroretinal (By similarity). Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change that activates signaling via G-proteins. Subsequent receptor phosphorylation mediates displacement of the bound G-protein alpha subunit by arrestin and terminates signaling (By similarity).
   
 0.972
RHO
Rhodopsin.
   
 0.972
H3DCF3_TETNG
Guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2.
  
 
0.937
H3CLF1_TETNG
Phosphodiesterase.
   
 0.823
H3CUR1_TETNG
Phosphodiesterase.
   
 0.792
GRK1
G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.
   
 0.782
H3D005_TETNG
Guanine nucleotide binding protein (G protein), beta polypeptide 1a.
   
 0.772
Your Current Organism:
Tetraodon nigroviridis
NCBI taxonomy Id: 99883
Other names: T. nigroviridis, spotted green pufferfish
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