STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Q4RRQ1_TETNGChromosome 16 SCAF15002, whole genome shotgun sequence; Belongs to the serpin family. (178 aa)    
Predicted Functional Partners:
H3C6P0_TETNG
Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...]
  
 0.867
H3CM77_TETNG
Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.
  
 0.703
H3C7P2_TETNG
Fibrinogen alpha chain.
   
 
 0.686
H3C4D6_TETNG
Uncharacterized protein.
  
 0.635
H3CC24_TETNG
Serpin peptidase inhibitor, clade C (antithrombin), member 1; Belongs to the serpin family.
  
  
0.619
H3CWF9_TETNG
SERPIN domain-containing protein; Belongs to the serpin family.
  
  
 0.595
H3CN11_TETNG
SERPIN domain-containing protein; Belongs to the serpin family.
  
  
 0.594
H3CQF7_TETNG
SERPIN domain-containing protein; Belongs to the serpin family.
  
  
 0.594
APOH
Apolipoprotein H.
   
 
 0.589
H3C6Y6_TETNG
Alpha-1-microglobulin/bikunin precursor.
   
 
 0.577
Your Current Organism:
Tetraodon nigroviridis
NCBI taxonomy Id: 99883
Other names: T. nigroviridis, spotted green pufferfish
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