STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
H3DM34_TETNGThyroid hormone receptor interactor 13; Belongs to the AAA ATPase family. (427 aa)    
Predicted Functional Partners:
H3CLE6_TETNG
MAD2 mitotic arrest deficient-like 1 (yeast).
   
 
 0.972
H3DCQ5_TETNG
UBX domain-containing protein 7.
   
 0.965
H3C2M4_TETNG
MAD2L1 binding protein.
   
 
 0.962
H3D002_TETNG
Mitotic arrest deficient 2 like 2.
    
 
 0.928
H3BW05_TETNG
Non-specific serine/threonine protein kinase.
   
  
 0.911
H3CFH1_TETNG
Exonuclease 1.
  
  
 0.910
H3DCT0_TETNG
Cell division cycle 20 homolog.
  
 
 0.865
H3DCT1_TETNG
Cell division cycle 20 homolog.
  
 
 0.865
MCM7
DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]
   
 
 0.851
H3CPL0_TETNG
UF2 component of NDC80 kinetochore complex.
   
  
 0.841
Your Current Organism:
Tetraodon nigroviridis
NCBI taxonomy Id: 99883
Other names: T. nigroviridis, spotted green pufferfish
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.