STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
H3DRG7_TETNGG protein-coupled receptor kinase 7b. (441 aa)    
Predicted Functional Partners:
Q4RYG1_TETNG
Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
   
 0.600
H3BZD6_TETNG
G_PROTEIN_RECEP_F1_2 domain-containing protein.
   
 0.578
H3C2G0_TETNG
Rhodopsin.
   
 0.578
rho
Rhodopsin; Photoreceptor required for image-forming vision at low light intensity. While most salt water fish species use retinal as chromophore, most freshwater fish use 3-dehydroretinal, or a mixture of retinal and 3-dehydroretinal (By similarity). Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change that activates signaling via G-proteins. Subsequent receptor phosphorylation mediates displacement of the bound G-protein alpha subunit by arrestin and terminates signaling (By similarity).
   
 0.578
RHO
Rhodopsin.
   
 0.578
H3D005_TETNG
Guanine nucleotide binding protein (G protein), beta polypeptide 1a.
   
 0.534
H3D2I5_TETNG
Guanine nucleotide binding protein (G protein), beta polypeptide 2.
   
 0.534
Q4RX95_TETNG
Guanine nucleotide binding protein (G protein), beta polypeptide 1b.
   
 0.534
H3DDM6_TETNG
Guanine nucleotide binding protein (G protein), beta polypeptide 4b.
   
 0.534
H3CRG4_TETNG
Guanine nucleotide binding protein (G protein), beta polypeptide 3a.
   
 0.511
Your Current Organism:
Tetraodon nigroviridis
NCBI taxonomy Id: 99883
Other names: T. nigroviridis, spotted green pufferfish
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