node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
GME_08624 | GME_10886 | GME_08624 | GME_10886 | Diguanylate cyclase/phosphodiesterase with GAF sensor; COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain. | Beta-lactamase-like protein; COG0595 Predicted hydrolase of the metallo-beta-lactamase superfamily. | 0.480 |
GME_08624 | rsmA | GME_08624 | GME_00745 | Diguanylate cyclase/phosphodiesterase with GAF sensor; COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain. | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | 0.457 |
GME_09621 | GME_10886 | GME_09621 | GME_10886 | Polyprenyl synthetase; COG0142 Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family. | Beta-lactamase-like protein; COG0595 Predicted hydrolase of the metallo-beta-lactamase superfamily. | 0.752 |
GME_09621 | GME_12818 | GME_09621 | GME_12818 | Polyprenyl synthetase; COG0142 Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family. | Octylprenyl diphosphate synthase; COG0142 Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family. | 0.938 |
GME_10876 | GME_10886 | GME_10876 | GME_10886 | COG3235 Predicted membrane protein. | Beta-lactamase-like protein; COG0595 Predicted hydrolase of the metallo-beta-lactamase superfamily. | 0.639 |
GME_10876 | purU | GME_10876 | GME_10881 | COG3235 Predicted membrane protein. | Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). | 0.768 |
GME_10886 | GME_08624 | GME_10886 | GME_08624 | Beta-lactamase-like protein; COG0595 Predicted hydrolase of the metallo-beta-lactamase superfamily. | Diguanylate cyclase/phosphodiesterase with GAF sensor; COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain. | 0.480 |
GME_10886 | GME_09621 | GME_10886 | GME_09621 | Beta-lactamase-like protein; COG0595 Predicted hydrolase of the metallo-beta-lactamase superfamily. | Polyprenyl synthetase; COG0142 Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family. | 0.752 |
GME_10886 | GME_10876 | GME_10886 | GME_10876 | Beta-lactamase-like protein; COG0595 Predicted hydrolase of the metallo-beta-lactamase superfamily. | COG3235 Predicted membrane protein. | 0.639 |
GME_10886 | GME_12818 | GME_10886 | GME_12818 | Beta-lactamase-like protein; COG0595 Predicted hydrolase of the metallo-beta-lactamase superfamily. | Octylprenyl diphosphate synthase; COG0142 Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family. | 0.752 |
GME_10886 | purU | GME_10886 | GME_10881 | Beta-lactamase-like protein; COG0595 Predicted hydrolase of the metallo-beta-lactamase superfamily. | Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). | 0.687 |
GME_10886 | rnpA | GME_10886 | GME_10516 | Beta-lactamase-like protein; COG0595 Predicted hydrolase of the metallo-beta-lactamase superfamily. | Ribonuclease P; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. | 0.628 |
GME_10886 | rnr | GME_10886 | GME_02044 | Beta-lactamase-like protein; COG0595 Predicted hydrolase of the metallo-beta-lactamase superfamily. | Ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. | 0.480 |
GME_10886 | rsmA | GME_10886 | GME_00745 | Beta-lactamase-like protein; COG0595 Predicted hydrolase of the metallo-beta-lactamase superfamily. | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | 0.604 |
GME_10886 | topA | GME_10886 | GME_11402 | Beta-lactamase-like protein; COG0595 Predicted hydrolase of the metallo-beta-lactamase superfamily. | DNA topoisomerase I subunit omega; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus rem [...] | 0.559 |
GME_10886 | ybeY | GME_10886 | GME_06874 | Beta-lactamase-like protein; COG0595 Predicted hydrolase of the metallo-beta-lactamase superfamily. | Hypothetical protein; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. | 0.542 |
GME_12818 | GME_09621 | GME_12818 | GME_09621 | Octylprenyl diphosphate synthase; COG0142 Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family. | Polyprenyl synthetase; COG0142 Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family. | 0.938 |
GME_12818 | GME_10886 | GME_12818 | GME_10886 | Octylprenyl diphosphate synthase; COG0142 Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family. | Beta-lactamase-like protein; COG0595 Predicted hydrolase of the metallo-beta-lactamase superfamily. | 0.752 |
purU | GME_10876 | GME_10881 | GME_10876 | Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). | COG3235 Predicted membrane protein. | 0.768 |
purU | GME_10886 | GME_10881 | GME_10886 | Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). | Beta-lactamase-like protein; COG0595 Predicted hydrolase of the metallo-beta-lactamase superfamily. | 0.687 |