node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
GME_01037 | GME_05600 | GME_01037 | GME_05600 | Two-component hybrid sensor and regulator; COG2203 FOG: GAF domain. | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | 0.433 |
GME_01037 | GME_11792 | GME_01037 | GME_11792 | Two-component hybrid sensor and regulator; COG2203 FOG: GAF domain. | NUDIX hydrolase; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes. | 0.567 |
GME_01037 | gcvP | GME_01037 | GME_16317 | Two-component hybrid sensor and regulator; COG2203 FOG: GAF domain. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.472 |
GME_01037 | metH | GME_01037 | GME_15915 | Two-component hybrid sensor and regulator; COG2203 FOG: GAF domain. | B12-dependent methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.658 |
GME_05600 | GME_01037 | GME_05600 | GME_01037 | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | Two-component hybrid sensor and regulator; COG2203 FOG: GAF domain. | 0.433 |
GME_05600 | GME_11792 | GME_05600 | GME_11792 | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | NUDIX hydrolase; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes. | 0.591 |
GME_11772 | GME_11792 | GME_11772 | GME_11792 | ThiJ/PfpI; COG0693 Putative intracellular protease/amidase. | NUDIX hydrolase; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes. | 0.436 |
GME_11782 | GME_11787 | GME_11782 | GME_11787 | Glutathione-dependent formaldehyde-activating, GFA. | Acetyltransferase (GNAT) family protein; COG0454 Histone acetyltransferase HPA2 and related acetyltransferases. | 0.608 |
GME_11782 | GME_11792 | GME_11782 | GME_11792 | Glutathione-dependent formaldehyde-activating, GFA. | NUDIX hydrolase; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes. | 0.517 |
GME_11787 | GME_11782 | GME_11787 | GME_11782 | Acetyltransferase (GNAT) family protein; COG0454 Histone acetyltransferase HPA2 and related acetyltransferases. | Glutathione-dependent formaldehyde-activating, GFA. | 0.608 |
GME_11787 | GME_11792 | GME_11787 | GME_11792 | Acetyltransferase (GNAT) family protein; COG0454 Histone acetyltransferase HPA2 and related acetyltransferases. | NUDIX hydrolase; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes. | 0.652 |
GME_11787 | GME_11797 | GME_11787 | GME_11797 | Acetyltransferase (GNAT) family protein; COG0454 Histone acetyltransferase HPA2 and related acetyltransferases. | Hypothetical protein; COG0454 Histone acetyltransferase HPA2 and related acetyltransferases. | 0.424 |
GME_11792 | GME_01037 | GME_11792 | GME_01037 | NUDIX hydrolase; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes. | Two-component hybrid sensor and regulator; COG2203 FOG: GAF domain. | 0.567 |
GME_11792 | GME_05600 | GME_11792 | GME_05600 | NUDIX hydrolase; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes. | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | 0.591 |
GME_11792 | GME_11772 | GME_11792 | GME_11772 | NUDIX hydrolase; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes. | ThiJ/PfpI; COG0693 Putative intracellular protease/amidase. | 0.436 |
GME_11792 | GME_11782 | GME_11792 | GME_11782 | NUDIX hydrolase; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes. | Glutathione-dependent formaldehyde-activating, GFA. | 0.517 |
GME_11792 | GME_11787 | GME_11792 | GME_11787 | NUDIX hydrolase; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes. | Acetyltransferase (GNAT) family protein; COG0454 Histone acetyltransferase HPA2 and related acetyltransferases. | 0.652 |
GME_11792 | GME_11797 | GME_11792 | GME_11797 | NUDIX hydrolase; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes. | Hypothetical protein; COG0454 Histone acetyltransferase HPA2 and related acetyltransferases. | 0.493 |
GME_11792 | GME_16172 | GME_11792 | GME_16172 | NUDIX hydrolase; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes. | Fumarate hydratase, class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 0.582 |
GME_11792 | gcvP | GME_11792 | GME_16317 | NUDIX hydrolase; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.657 |