STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ntrCTwo-component response regulator NtrC; Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes. (476 aa)    
Predicted Functional Partners:
GME_13090
COG3852 Signal transduction histidine kinase, nitrogen specific.
 0.999
GME_04127
COG0642 Signal transduction histidine kinase.
  
 0.958
GME_01042
PAS sensor protein; COG5002 Signal transduction histidine kinase.
 
 0.943
GME_00640
Multi-sensor hybrid histidine kinase; COG2203 FOG: GAF domain.
  
 0.930
GME_00050
Two-component sensor; COG0591 Na+/proline symporter.
  
 0.917
GME_03537
RNA polymerase sigma-54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
  
 0.890
GME_08054
CheA signal transduction histidine kinase; COG0643 Chemotaxis protein histidine kinase and related kinases.
  
 0.880
GME_00315
COG0642 Signal transduction histidine kinase.
  
 0.874
GME_08064
COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain.
  
 0.859
GME_08624
Diguanylate cyclase/phosphodiesterase with GAF sensor; COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain.
  
 0.841
Your Current Organism:
Halomonas sp. TD01
NCBI taxonomy Id: 999141
Other names: H. sp. TD01
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