Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SQLESqualene epoxidase. (574 aa)    
Predicted Functional Partners:
LSS
Lanosterol synthase.
 
 
 0.994
CYP51A1
Cytochrome P450 family 51 subfamily A member 1.
 
 0.993
NSDHL
NAD(P) dependent steroid dehydrogenase-like.
   
 
 0.991
DHCR7
7-dehydrocholesterol reductase.
   
 
 0.983
ENSMMMP00000004599
annotation not available
   
 0.983
CH25H
Cholesterol 25-hydroxylase.
   
 0.983
ENSMMMP00000017125
annotation not available
   
 0.983
FDFT1
Farnesyl-diphosphate farnesyltransferase 1.
 
 
 0.975
FAXDC2
Fatty acid hydroxylase domain containing 2.
   
 0.975
ENSMMMP00000008823
annotation not available
 
 
 0.974
Your Current Organism:
Marmota marmota
NCBI taxonomy Id: 9994
Other names: Alpine marmot, M. marmota marmota, Marmota marmota marmota
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