Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
USP40Ubiquitin specific peptidase 40. (1234 aa)    
Predicted Functional Partners:
TRIP12
Thyroid hormone receptor interactor 12.
   
 
 0.944
TP53
Tumor protein p53.
    
 0.943
UVSSA
UV stimulated scaffold protein A.
    
 0.928
DAXX
Death domain associated protein.
    
 0.912
GMPS
Guanine monophosphate synthase.
   
 
 0.898
TRAF6
TNF receptor associated factor 6.
    
 0.870
HID1
HID1 domain containing.
    
 
 0.851
DNMT1
DNA methyltransferase 1.
   
 
 0.828
PPM1G
Protein phosphatase, Mg2+/Mn2+ dependent 1G.
   
 0.828
CHEK1
Checkpoint kinase 1.
    
 
 0.801
Your Current Organism:
Marmota marmota
NCBI taxonomy Id: 9994
Other names: Alpine marmot, M. marmota marmota, Marmota marmota marmota
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