Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSMMMP00000004599annotation not available (292 aa)    
Predicted Functional Partners:
SC5D
sterol-C5-desaturase.
   
 0.989
CYP51A1
Cytochrome P450 family 51 subfamily A member 1.
   
 0.988
NSDHL
NAD(P) dependent steroid dehydrogenase-like.
  
 0.987
SQLE
Squalene epoxidase.
   
 0.983
CYP7B1
Cytochrome P450 family 7 subfamily B member 1.
   
 0.981
HSD17B7
Hydroxysteroid 17-beta dehydrogenase 7.
   
 0.981
CYP7A1
Cytochrome P450 family 7 subfamily A member 1.
   
 0.974
DHCR7
7-dehydrocholesterol reductase.
   
 0.963
SIGMAR1
Sigma non-opioid intracellular receptor 1.
   
 0.961
TM7SF2
Transmembrane 7 superfamily member 2.
   
 0.957
Your Current Organism:
Marmota marmota
NCBI taxonomy Id: 9994
Other names: Alpine marmot, M. marmota marmota, Marmota marmota marmota
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