Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
E2F8E2F transcription factor 8. (867 aa)    
Predicted Functional Partners:
E2F7
E2F transcription factor 7.
   
 0.988
KIF11
Kinesin family member 11.
   
  
 0.954
ENSMMMP00000024068
annotation not available
   
  
 0.938
TTK
TTK protein kinase.
   
  
 0.922
KIF15
Kinesin family member 15.
   
  
 0.919
KIF20A
Kinesin family member 20A.
   
  
 0.902
ENSMMMP00000003156
annotation not available
   
  
 0.880
TOP2A
DNA topoisomerase II alpha.
   
  
 0.880
CCNA2
Cyclin A2.
   
 
 0.879
ENSMMMP00000005433
annotation not available
   
  
 0.865
Your Current Organism:
Marmota marmota
NCBI taxonomy Id: 9994
Other names: Alpine marmot, M. marmota marmota, Marmota marmota marmota
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