STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GSK3BGlycogen synthase kinase 3 beta. (433 aa)    
Predicted Functional Partners:
AXIN1
Axin 1.
   
 0.995
CTNNB1
Catenin beta 1.
    
 0.994
MAPT
Microtubule associated protein tau.
    
 0.987
APC
APC regulator of WNT signaling pathway.
    
 0.984
AXIN2
Axin 2.
   
 0.979
AKT1
AKT serine/threonine kinase 1.
    
0.978
BTRC
Beta-transducin repeat containing E3 ubiquitin protein ligase.
    
 0.978
FRAT2
FRAT regulator of WNT signaling pathway 2.
    
 0.969
MYC
MYC proto-oncogene, bHLH transcription factor.
    
 0.964
TRAF6
TNF receptor associated factor 6.
    
 0.952
Your Current Organism:
Marmota marmota
NCBI taxonomy Id: 9994
Other names: Alpine marmot, M. marmota marmota, Marmota marmota marmota
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.