STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LDLRAP1Low density lipoprotein receptor adaptor protein 1. (278 aa)    
Predicted Functional Partners:
LDLR
Low density lipoprotein receptor.
    
 0.988
AP2B1
Adaptor related protein complex 2 subunit beta 1.
    
 0.985
ITSN2
Intersectin 2.
    
 0.977
LRP2
LDL receptor related protein 2.
    
 0.962
AP1B1
Adaptor related protein complex 1 subunit beta 1.
    
 0.937
VLDLR
Very low density lipoprotein receptor.
    
 0.916
LRP8
LDL receptor related protein 8.
    
 0.916
APPL1
Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1.
    
 
 0.898
APPL2
Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2.
    
 
 0.898
AP4B1
Adaptor related protein complex 4 subunit beta 1.
    
 0.890
Your Current Organism:
Marmota marmota
NCBI taxonomy Id: 9994
Other names: Alpine marmot, M. marmota marmota, Marmota marmota marmota
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.