STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ESR2Estrogen receptor 2. (567 aa)    
Predicted Functional Partners:
NCOA1
Nuclear receptor coactivator 1.
    
 0.998
ESR1
Estrogen receptor 1.
  
 
0.985
NCOA2
Nuclear receptor coactivator 2.
    
 0.983
NCOA3
Nuclear receptor coactivator 3.
    
 0.980
SP1
Sp1 transcription factor.
    
 0.976
MED1
Mediator complex subunit 1.
    
 0.959
NCOR1
Nuclear receptor corepressor 1.
    
 0.944
JUN
Jun proto-oncogene, AP-1 transcription factor subunit.
    
 0.939
EP300
E1A binding protein p300.
    
 0.937
FOS
Fos proto-oncogene, AP-1 transcription factor subunit.
    
 0.933
Your Current Organism:
Marmota marmota
NCBI taxonomy Id: 9994
Other names: Alpine marmot, M. marmota marmota, Marmota marmota marmota
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.