STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SIK3SIK family kinase 3. (1369 aa)    
Predicted Functional Partners:
CRTC3
CREB regulated transcription coactivator 3.
    
 0.848
CRTC2
CREB regulated transcription coactivator 2.
    
 0.840
PLA2G4A
Phospholipase A2 group IVA.
    
 0.729
SCGN
Secretagogin, EF-hand calcium binding protein.
   
 0.670
CASK
Calcium/calmodulin dependent serine protein kinase.
   
0.622
RIPK4
Receptor interacting serine/threonine kinase 4.
    
0.571
TSHR
Thyroid stimulating hormone receptor.
     
 0.570
DMBX1
Diencephalon/mesencephalon homeobox 1.
      
 0.567
CCDC91
Coiled-coil domain containing 91.
   
 0.548
CRTC1
CREB regulated transcription coactivator 1.
     
 0.545
Your Current Organism:
Marmota marmota
NCBI taxonomy Id: 9994
Other names: Alpine marmot, M. marmota marmota, Marmota marmota marmota
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.