| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EKU70568.1 | EKU70569.1 | HMPREF9161_01614 | HMPREF9161_01615 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Riboflavin synthase, alpha subunit. | 0.999 |
| EKU70568.1 | EKU70572.1 | HMPREF9161_01614 | HMPREF9161_01618 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | MJ0936 family phosphodiesterase. | 0.840 |
| EKU70568.1 | EKU70574.1 | HMPREF9161_01614 | HMPREF9161_01620 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Hypothetical protein. | 0.717 |
| EKU70568.1 | EKU71619.1 | HMPREF9161_01614 | HMPREF9161_00304 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | HAD hydrolase, family IA. | 0.642 |
| EKU70568.1 | EKU71634.1 | HMPREF9161_01614 | HMPREF9161_00319 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Hypothetical protein. | 0.701 |
| EKU70568.1 | eno | HMPREF9161_01614 | HMPREF9161_01624 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | 0.782 |
| EKU70568.1 | folE | HMPREF9161_01614 | HMPREF9161_00130 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | GTP cyclohydrolase I. | 0.669 |
| EKU70568.1 | hslO | HMPREF9161_01614 | HMPREF9161_01619 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Hypothetical protein; Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress. | 0.808 |
| EKU70568.1 | ribBA | HMPREF9161_01614 | HMPREF9161_01616 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.999 |
| EKU70568.1 | ribH | HMPREF9161_01614 | HMPREF9161_01617 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.991 |
| EKU70569.1 | EKU70568.1 | HMPREF9161_01615 | HMPREF9161_01614 | Riboflavin synthase, alpha subunit. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.999 |
| EKU70569.1 | EKU70572.1 | HMPREF9161_01615 | HMPREF9161_01618 | Riboflavin synthase, alpha subunit. | MJ0936 family phosphodiesterase. | 0.846 |
| EKU70569.1 | EKU70574.1 | HMPREF9161_01615 | HMPREF9161_01620 | Riboflavin synthase, alpha subunit. | Hypothetical protein. | 0.725 |
| EKU70569.1 | EKU71619.1 | HMPREF9161_01615 | HMPREF9161_00304 | Riboflavin synthase, alpha subunit. | HAD hydrolase, family IA. | 0.600 |
| EKU70569.1 | folE | HMPREF9161_01615 | HMPREF9161_00130 | Riboflavin synthase, alpha subunit. | GTP cyclohydrolase I. | 0.527 |
| EKU70569.1 | hslO | HMPREF9161_01615 | HMPREF9161_01619 | Riboflavin synthase, alpha subunit. | Hypothetical protein; Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress. | 0.814 |
| EKU70569.1 | ribBA | HMPREF9161_01615 | HMPREF9161_01616 | Riboflavin synthase, alpha subunit. | GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.999 |
| EKU70569.1 | ribH | HMPREF9161_01615 | HMPREF9161_01617 | Riboflavin synthase, alpha subunit. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.999 |
| EKU70572.1 | EKU70568.1 | HMPREF9161_01618 | HMPREF9161_01614 | MJ0936 family phosphodiesterase. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.840 |
| EKU70572.1 | EKU70569.1 | HMPREF9161_01618 | HMPREF9161_01615 | MJ0936 family phosphodiesterase. | Riboflavin synthase, alpha subunit. | 0.846 |
