node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AEA58817.1 | AEA63141.1 | bgla_1g01160 | bgla_2g06670 | L-serine ammonia-lyase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Sarcosine oxidase, alpha subunit family protein; Belongs to the GcvT family. | 0.596 |
AEA58817.1 | gcvH | bgla_1g01160 | bgla_1g01190 | L-serine ammonia-lyase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.555 |
AEA58817.1 | gcvP | bgla_1g01160 | bgla_1g01180 | L-serine ammonia-lyase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.813 |
AEA58817.1 | gcvT | bgla_1g01160 | bgla_1g01200 | L-serine ammonia-lyase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine. | 0.604 |
AEA58817.1 | glyA | bgla_1g01160 | bgla_1g07320 | L-serine ammonia-lyase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.946 |
AEA61419.1 | AEA63141.1 | bgla_1g28040 | bgla_2g06670 | Dihydrolipoamide dehydrogenase. | Sarcosine oxidase, alpha subunit family protein; Belongs to the GcvT family. | 0.954 |
AEA61419.1 | folD | bgla_1g28040 | bgla_1g28090 | Dihydrolipoamide dehydrogenase. | Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.567 |
AEA61419.1 | gcvH | bgla_1g28040 | bgla_1g01190 | Dihydrolipoamide dehydrogenase. | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.998 |
AEA61419.1 | gcvP | bgla_1g28040 | bgla_1g01180 | Dihydrolipoamide dehydrogenase. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.983 |
AEA61419.1 | gcvT | bgla_1g28040 | bgla_1g01200 | Dihydrolipoamide dehydrogenase. | Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine. | 0.994 |
AEA61419.1 | glyA | bgla_1g28040 | bgla_1g07320 | Dihydrolipoamide dehydrogenase. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.953 |
AEA61419.1 | purL | bgla_1g28040 | bgla_1g23820 | Dihydrolipoamide dehydrogenase. | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.587 |
AEA63141.1 | AEA58817.1 | bgla_2g06670 | bgla_1g01160 | Sarcosine oxidase, alpha subunit family protein; Belongs to the GcvT family. | L-serine ammonia-lyase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.596 |
AEA63141.1 | AEA61419.1 | bgla_2g06670 | bgla_1g28040 | Sarcosine oxidase, alpha subunit family protein; Belongs to the GcvT family. | Dihydrolipoamide dehydrogenase. | 0.954 |
AEA63141.1 | folD | bgla_2g06670 | bgla_1g28090 | Sarcosine oxidase, alpha subunit family protein; Belongs to the GcvT family. | Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.678 |
AEA63141.1 | gcvH | bgla_2g06670 | bgla_1g01190 | Sarcosine oxidase, alpha subunit family protein; Belongs to the GcvT family. | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.965 |
AEA63141.1 | gcvP | bgla_2g06670 | bgla_1g01180 | Sarcosine oxidase, alpha subunit family protein; Belongs to the GcvT family. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.997 |
AEA63141.1 | glyA | bgla_2g06670 | bgla_1g07320 | Sarcosine oxidase, alpha subunit family protein; Belongs to the GcvT family. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.970 |
AEA63141.1 | purL | bgla_2g06670 | bgla_1g23820 | Sarcosine oxidase, alpha subunit family protein; Belongs to the GcvT family. | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.462 |
folD | AEA61419.1 | bgla_1g28090 | bgla_1g28040 | Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | Dihydrolipoamide dehydrogenase. | 0.567 |