STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEA63254.1KpsF/GutQ family protein; Belongs to the SIS family. GutQ/KpsF subfamily. (311 aa)    
Predicted Functional Partners:
kdsA-2
2-dehydro-3-deoxyphosphooctonate aldolase; Belongs to the KdsA family.
 
 
 0.997
kdsA
2-dehydro-3-deoxyphosphooctonate aldolase; Belongs to the KdsA family.
 
 
 0.988
AEA63252.1
3-deoxy-D-manno-octulosonate 8-phosphate phosphatase.
  
 0.972
kdsB-2
3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
 
   
 0.970
AEA62085.1
Sugar isomerase, KpsF/GutQ family protein; Belongs to the SIS family. GutQ/KpsF subfamily.
 
  
0.914
AEA62086.1
3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family protein.
  
 0.894
kdsB
CMP-2-keto-3-deoxyoctulosonic acid synthetase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
 
   
 0.874
lpxK
Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
 
   
 0.862
AEA59499.1
3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family.
 
   
 0.847
lpxA
UDP-N-acetylglucosamine acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
 
 
 0.845
Your Current Organism:
Burkholderia gladioli
NCBI taxonomy Id: 999541
Other names: B. gladioli BSR3, Burkholderia gladioli BSR3, Burkholderia gladioli str. BSR3, Burkholderia gladioli strain BSR3
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.