node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AHC99883.1 | AHC99884.1 | METH_03340 | METH_03345 | Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.999 |
AHC99883.1 | AHC99885.1 | METH_03340 | METH_03350 | Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | 0.999 |
AHC99883.1 | AHD00379.1 | METH_03340 | METH_06230 | Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | FAD-dependent pyridine nucleotide-disulfide oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.972 |
AHC99883.1 | AHD02267.1 | METH_03340 | METH_18085 | Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | NADH-quinone oxidoreductase subunit F; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.950 |
AHC99883.1 | fumC | METH_03340 | METH_10450 | Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | 0.960 |
AHC99883.1 | gabD | METH_03340 | METH_15325 | Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Succinate-semialdehyde dehdyrogenase; Catalyzes the formation of succinate from succinate semialdehyde; NADP dependent; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.904 |
AHC99883.1 | sdhB | METH_03340 | METH_03355 | Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.999 |
AHC99883.1 | sucA | METH_03340 | METH_03270 | Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | MFS transporter; SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.912 |
AHC99883.1 | sucC | METH_03340 | METH_03290 | Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | malate--CoA ligase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.977 |
AHC99883.1 | sucD | METH_03340 | METH_03280 | Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | succinyl-CoA synthetase subsunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.970 |
AHC99884.1 | AHC99883.1 | METH_03345 | METH_03340 | Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.999 |
AHC99884.1 | AHC99885.1 | METH_03345 | METH_03350 | Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | 0.997 |
AHC99884.1 | AHD00379.1 | METH_03345 | METH_06230 | Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | FAD-dependent pyridine nucleotide-disulfide oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.859 |
AHC99884.1 | AHD02267.1 | METH_03345 | METH_18085 | Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | NADH-quinone oxidoreductase subunit F; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.479 |
AHC99884.1 | fumC | METH_03345 | METH_10450 | Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | 0.921 |
AHC99884.1 | gabD | METH_03345 | METH_15325 | Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Succinate-semialdehyde dehdyrogenase; Catalyzes the formation of succinate from succinate semialdehyde; NADP dependent; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.904 |
AHC99884.1 | sdhB | METH_03345 | METH_03355 | Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.999 |
AHC99884.1 | sucA | METH_03345 | METH_03270 | Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | MFS transporter; SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.828 |
AHC99884.1 | sucC | METH_03345 | METH_03290 | Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | malate--CoA ligase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.974 |
AHC99884.1 | sucD | METH_03345 | METH_03280 | Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | succinyl-CoA synthetase subsunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.931 |