STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AHD00401.1Glyoxalase; Derived by automated computational analysis using gene prediction method: Protein Homology. (142 aa)    
Predicted Functional Partners:
gloB
Hydroxyacylglutathione hydrolase; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid.
 
  
 0.953
AHD02066.1
Ni-dependent; catalyzes the formation of S-lactoylglutathione from methylglyoxal and glutathione; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 
0.917
AHC99356.1
Metallo-beta-lactamase/rhodanese-like domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.908
AHC99589.1
Hydroxyacid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.902
AHD01668.1
2-hydroxyacid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.902
AHC99674.1
Serine/threonine dehydratase; Catalyzes the formation of 2-oxobutanoate from L-threonine or the formation of pyruvate from serine; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.822
ilvA
Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
   
 0.822
AHD02779.1
Threonine dehydratase; Catalyzes the formation of 2-oxobutanoate from L-threonine; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.822
trpB
Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
   
  0.821
AHD00259.1
Serine ammonia-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the iron-sulfur dependent L-serine dehydratase family.
   
 
  0.801
Your Current Organism:
Leisingera methylohalidivorans
NCBI taxonomy Id: 999552
Other names: L. methylohalidivorans DSM 14336, Leisingera methylohalidivorans DSM 14336, Leisingera methylohalidivorans MB2, Leisingera methylohalidivorans str. DSM 14336, Leisingera methylohalidivorans strain DSM 14336
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.