STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AHD00491.1acyl-CoA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (629 aa)    
Predicted Functional Partners:
AHD00816.1
Methylmalonate-semialdehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.928
AHD00358.1
methylmalonyl-CoA carboxyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.917
AHD01333.1
AMP-dependent synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 
0.917
AHD00365.1
acetyl-CoA carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.914
AHD01800.1
Phosphotransacetylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.914
acsA
acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
  
 
0.912
AHD00505.1
3-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.910
AHD01040.1
Quinone oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.908
AHD01719.1
CoA transferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.908
AHC99920.1
acetyl-CoA acetyltransferase; Catalyzes the thiolytic cleavage of beta-ketoadipyl-CoA to succinate and acetyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.857
Your Current Organism:
Leisingera methylohalidivorans
NCBI taxonomy Id: 999552
Other names: L. methylohalidivorans DSM 14336, Leisingera methylohalidivorans DSM 14336, Leisingera methylohalidivorans MB2, Leisingera methylohalidivorans str. DSM 14336, Leisingera methylohalidivorans strain DSM 14336
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