SFT54660.1 protein (Sedimentitalea nanhaiensis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

SFT54660.1

Amino acid/amide ABC transporter membrane protein 2, HAAT family; Belongs to the binding-protein-dependent transport system permease family. (358 aa)

Predicted Functional Partners:

SFT54680.1

0.996

SFT54699.1

0.983

SFT54641.1

0.976

SFT72754.1

0.971

SFT71305.1

0.968

SFT54622.1

0.951

SFT71332.1

0.947

SFT72731.1

0.945

SFU02197.1

0.933

SFT94080.1

0.912

Your Current Organism:

Sedimentitalea nanhaiensis

NCBI taxonomy Id: 999627
Other names: CCTCC AB 208316, DSM 24252, LMG 24841, LMG:24841, Leisingera nanhaiensis, Leisingera nanhaiensis Sun et al. 2010, MCCC 1A04178, S. nanhaiensis, Sedimentitalea nanhaiensis (Sun et al. 2010) Breider et al. 2014, strain NH52F

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SFT54622.1	SFT54641.1	SAMN05216236_10365	SAMN05216236_10366	Amino acid/amide ABC transporter ATP-binding protein 2, HAAT family.	Amino acid/amide ABC transporter substrate-binding protein, HAAT family.	0.955
SFT54622.1	SFT54660.1	SAMN05216236_10365	SAMN05216236_10367	Amino acid/amide ABC transporter ATP-binding protein 2, HAAT family.	Amino acid/amide ABC transporter membrane protein 2, HAAT family; Belongs to the binding-protein-dependent transport system permease family.	0.951
SFT54622.1	SFT54680.1	SAMN05216236_10365	SAMN05216236_10368	Amino acid/amide ABC transporter ATP-binding protein 2, HAAT family.	Amino acid/amide ABC transporter membrane protein 1, HAAT family; Belongs to the binding-protein-dependent transport system permease family.	0.897
SFT54622.1	SFT54699.1	SAMN05216236_10365	SAMN05216236_10369	Amino acid/amide ABC transporter ATP-binding protein 2, HAAT family.	Amino acid/amide ABC transporter ATP-binding protein 1, HAAT family.	0.724
SFT54622.1	SFT71305.1	SAMN05216236_10365	SAMN05216236_1063	Amino acid/amide ABC transporter ATP-binding protein 2, HAAT family.	Amino acid/amide ABC transporter ATP-binding protein 1, HAAT family.	0.899
SFT54622.1	SFT71332.1	SAMN05216236_10365	SAMN05216236_1065	Amino acid/amide ABC transporter ATP-binding protein 2, HAAT family.	Amino acid/amide ABC transporter membrane protein 1, HAAT family; Belongs to the binding-protein-dependent transport system permease family.	0.857
SFT54622.1	SFT72731.1	SAMN05216236_10365	SAMN05216236_10699	Amino acid/amide ABC transporter ATP-binding protein 2, HAAT family.	Amino acid/amide ABC transporter membrane protein 1, HAAT family; Belongs to the binding-protein-dependent transport system permease family.	0.853
SFT54622.1	SFT72754.1	SAMN05216236_10365	SAMN05216236_106101	Amino acid/amide ABC transporter ATP-binding protein 2, HAAT family.	Amino acid/amide ABC transporter ATP-binding protein 1, HAAT family.	0.635
SFT54622.1	SFT94080.1	SAMN05216236_10365	SAMN05216236_11431	Amino acid/amide ABC transporter ATP-binding protein 2, HAAT family.	Amino acid/amide ABC transporter ATP-binding protein 1, HAAT family.	0.611
SFT54622.1	SFU02197.1	SAMN05216236_10365	SAMN05216236_11932	Amino acid/amide ABC transporter ATP-binding protein 2, HAAT family.	Amino acid/amide ABC transporter membrane protein 1, HAAT family; Belongs to the binding-protein-dependent transport system permease family.	0.780
SFT54641.1	SFT54622.1	SAMN05216236_10366	SAMN05216236_10365	Amino acid/amide ABC transporter substrate-binding protein, HAAT family.	Amino acid/amide ABC transporter ATP-binding protein 2, HAAT family.	0.955
SFT54641.1	SFT54660.1	SAMN05216236_10366	SAMN05216236_10367	Amino acid/amide ABC transporter substrate-binding protein, HAAT family.	Amino acid/amide ABC transporter membrane protein 2, HAAT family; Belongs to the binding-protein-dependent transport system permease family.	0.976
SFT54641.1	SFT54680.1	SAMN05216236_10366	SAMN05216236_10368	Amino acid/amide ABC transporter substrate-binding protein, HAAT family.	Amino acid/amide ABC transporter membrane protein 1, HAAT family; Belongs to the binding-protein-dependent transport system permease family.	0.951
SFT54641.1	SFT54699.1	SAMN05216236_10366	SAMN05216236_10369	Amino acid/amide ABC transporter substrate-binding protein, HAAT family.	Amino acid/amide ABC transporter ATP-binding protein 1, HAAT family.	0.947
SFT54641.1	SFT71305.1	SAMN05216236_10366	SAMN05216236_1063	Amino acid/amide ABC transporter substrate-binding protein, HAAT family.	Amino acid/amide ABC transporter ATP-binding protein 1, HAAT family.	0.763
SFT54641.1	SFT71332.1	SAMN05216236_10366	SAMN05216236_1065	Amino acid/amide ABC transporter substrate-binding protein, HAAT family.	Amino acid/amide ABC transporter membrane protein 1, HAAT family; Belongs to the binding-protein-dependent transport system permease family.	0.739
SFT54641.1	SFT72731.1	SAMN05216236_10366	SAMN05216236_10699	Amino acid/amide ABC transporter substrate-binding protein, HAAT family.	Amino acid/amide ABC transporter membrane protein 1, HAAT family; Belongs to the binding-protein-dependent transport system permease family.	0.687
SFT54641.1	SFT72754.1	SAMN05216236_10366	SAMN05216236_106101	Amino acid/amide ABC transporter substrate-binding protein, HAAT family.	Amino acid/amide ABC transporter ATP-binding protein 1, HAAT family.	0.781
SFT54641.1	SFT94080.1	SAMN05216236_10366	SAMN05216236_11431	Amino acid/amide ABC transporter substrate-binding protein, HAAT family.	Amino acid/amide ABC transporter ATP-binding protein 1, HAAT family.	0.694
SFT54641.1	SFU02197.1	SAMN05216236_10366	SAMN05216236_11932	Amino acid/amide ABC transporter substrate-binding protein, HAAT family.	Amino acid/amide ABC transporter membrane protein 1, HAAT family; Belongs to the binding-protein-dependent transport system permease family.	0.687

page 1 of 5

Network Stats

number of nodes:

10

number of edges:

38

average node degree:

7.6

avg. local clustering coefficient:

0.903

expected number of edges:

10

PPI enrichment p-value:

2.79e-12

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0031463

Cul3-RING ubiquitin ligase complex

4 of 40

2.26

2.57

9.83e-06

Reference Publications (PubMed)

publication

(year) title

count in network

strength

signal

false discovery rate

PMID:37495603

(2023) A ubiquitin-based effector-to-inhibitor switch coordinates early brain, craniofacial, and skin development.

3 of 26

2.33

0.87

0.0251

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:27170

Mostly uncharacterized, incl. Cerebellum maturation, and Telomeric loop formation

3 of 18

2.49

1.7

0.00072

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

CFA-8951664

Neddylation

5 of 214

1.63

1.71

0.00010

CFA-983168

Antigen processing: Ubiquitination & Proteasome degradation

4 of 280

1.42

0.95

0.0067

CFA-597592

Post-translational protein modification

6 of 1073

1.01

0.72

0.0067

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0031463

Cul3-RING ubiquitin ligase complex

3 of 31

2.25

1.53

0.0013

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0880

Kelch repeat

3 of 48

2.06

1.54

0.0010

KW-0677

Repeat

5 of 1186

0.89

0.47

0.0497

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00875

BTB And C-terminal Kelch

3 of 56

1.99

1.29

0.0031

SM00225

Broad-Complex, Tramtrack and Bric a brac

3 of 158

1.54

0.73

0.0316

Enrichment display settings

Enrichment analysis is still ongoing, please wait ...

Server load: low (22%) [HD]

Permalink

Network

Neighborhood

Databases

Fusion

Textmining

Cooccurrence

Experiments

Coexpression

© STRING Consortium 2025

Credits

Access

Info

About