STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nadKNAD+ kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (302 aa)    
Predicted Functional Partners:
SFU07194.1
NAD(P) transhydrogenase subunit alpha; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the AlaDH/PNT family.
     
 0.945
nadE
NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
    
 0.935
SFU07205.1
NAD(P) transhydrogenase subunit beta; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.
     
 0.929
nadD
Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
  
 
 0.920
cobB-2
NAD-dependent deacetylase; Belongs to the sirtuin family. Class III subfamily.
  
 
 0.908
SFT76475.1
ATP diphosphatase.
     
 0.863
SFU03237.1
NAD+ diphosphatase; Belongs to the Nudix hydrolase family.
     
 0.853
SFT90399.1
Malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+).
 
 
 0.705
SFU08940.1
Malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+).
 
 
 0.704
SFU13860.1
Malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+).
 
 
 0.701
Your Current Organism:
Sedimentitalea nanhaiensis
NCBI taxonomy Id: 999627
Other names: CCTCC AB 208316, DSM 24252, LMG 24841, LMG:24841, Leisingera nanhaiensis, Leisingera nanhaiensis Sun et al. 2010, MCCC 1A04178, S. nanhaiensis, Sedimentitalea nanhaiensis (Sun et al. 2010) Breider et al. 2014, strain NH52F
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.