node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SFT35291.1 | SFT37821.1 | SAMN05216236_101174 | SAMN05216236_101282 | Phosphoserine phosphatase. | Glyoxylate/hydroxypyruvate reductase A. | 0.534 |
SFT35291.1 | SFU21160.1 | SAMN05216236_101174 | SAMN05216236_1586 | Phosphoserine phosphatase. | Aspartate aminotransferase. | 0.874 |
SFT35291.1 | gcvP | SAMN05216236_101174 | SAMN05216236_11633 | Phosphoserine phosphatase. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.402 |
SFT35291.1 | glyA | SAMN05216236_101174 | SAMN05216236_1581 | Phosphoserine phosphatase. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.899 |
SFT37821.1 | SFT35291.1 | SAMN05216236_101282 | SAMN05216236_101174 | Glyoxylate/hydroxypyruvate reductase A. | Phosphoserine phosphatase. | 0.534 |
SFT37821.1 | SFU21152.1 | SAMN05216236_101282 | SAMN05216236_1583 | Glyoxylate/hydroxypyruvate reductase A. | Glyoxylate reductase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.731 |
SFT37821.1 | SFU21160.1 | SAMN05216236_101282 | SAMN05216236_1586 | Glyoxylate/hydroxypyruvate reductase A. | Aspartate aminotransferase. | 0.876 |
SFT37821.1 | glcB | SAMN05216236_101282 | SAMN05216236_12330 | Glyoxylate/hydroxypyruvate reductase A. | Malate synthase; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. | 0.871 |
SFT93946.1 | SFU21160.1 | SAMN05216236_11419 | SAMN05216236_1586 | Sarcosine oxidase subunit gamma. | Aspartate aminotransferase. | 0.878 |
SFT93946.1 | gcvP | SAMN05216236_11419 | SAMN05216236_11633 | Sarcosine oxidase subunit gamma. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.863 |
SFT93946.1 | glyA | SAMN05216236_11419 | SAMN05216236_1581 | Sarcosine oxidase subunit gamma. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.660 |
SFT98418.1 | SFU21160.1 | SAMN05216236_11684 | SAMN05216236_1586 | L-threonine aldolase. | Aspartate aminotransferase. | 0.866 |
SFT98418.1 | gcvP | SAMN05216236_11684 | SAMN05216236_11633 | L-threonine aldolase. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.957 |
SFT98418.1 | glyA | SAMN05216236_11684 | SAMN05216236_1581 | L-threonine aldolase. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.757 |
SFU21150.1 | SFU21152.1 | SAMN05216236_1582 | SAMN05216236_1583 | Phosphoenolpyruvate carboxylase, type 1; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. | Glyoxylate reductase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.883 |
SFU21150.1 | SFU21160.1 | SAMN05216236_1582 | SAMN05216236_1586 | Phosphoenolpyruvate carboxylase, type 1; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. | Aspartate aminotransferase. | 0.911 |
SFU21150.1 | SFU21162.1 | SAMN05216236_1582 | SAMN05216236_1587 | Phosphoenolpyruvate carboxylase, type 1; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. | Two component transcriptional regulator, LuxR family. | 0.722 |
SFU21150.1 | gcvP | SAMN05216236_1582 | SAMN05216236_11633 | Phosphoenolpyruvate carboxylase, type 1; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.408 |
SFU21150.1 | glcB | SAMN05216236_1582 | SAMN05216236_12330 | Phosphoenolpyruvate carboxylase, type 1; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. | Malate synthase; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. | 0.905 |
SFU21150.1 | glyA | SAMN05216236_1582 | SAMN05216236_1581 | Phosphoenolpyruvate carboxylase, type 1; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.787 |