STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hemEUroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. (346 aa)    
Predicted Functional Partners:
hemC
Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
 0.999
SFT54950.1
Coproporphyrinogen oxidase.
 
 0.983
hemH
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.
 
  
 0.982
SFT36610.1
Oxygen-independent coproporphyrinogen-3 oxidase; Belongs to the anaerobic coproporphyrinogen-III oxidase family.
 
 
 0.971
SFT96433.1
uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.
  
 
 0.920
SFU16822.1
Glutamate synthase (NADPH) large subunit.
 
  
 0.864
SFT50277.1
Porphobilinogen synthase; Belongs to the ALAD family.
 
 
 0.779
SFT38791.1
uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family.
    
 0.757
SFT89578.1
uroporphyrinogen-III C-methyltransferase.
    
 0.757
rho
Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template.
   
 0.724
Your Current Organism:
Sedimentitalea nanhaiensis
NCBI taxonomy Id: 999627
Other names: CCTCC AB 208316, DSM 24252, LMG 24841, LMG:24841, Leisingera nanhaiensis, Leisingera nanhaiensis Sun et al. 2010, MCCC 1A04178, S. nanhaiensis, Sedimentitalea nanhaiensis (Sun et al. 2010) Breider et al. 2014, strain NH52F
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