STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TUZN_0756CopG family transcriptional regulator. (50 aa)    
Predicted Functional Partners:
cobB
NAD-dependent deacetylase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription; Belongs to the sirtuin family. Class U subfamily.
   
    0.533
cobB-2
NAD-dependent deacetylase; Belongs to the sirtuin family. Class III subfamily.
   
    0.533
TUZN_0757
Hypothetical protein.
       0.505
TUZN_0758
Hypothetical protein.
       0.469
TUZN_0845
Nicotinamide-nucleotide adenylyltransferase.
  
    0.463
TUZN_1939
Cytidyltransferase-related domain protein.
  
    0.463
TUZN_0755
FAD-dependent pyridine nucleotide-disulfide oxidoreductase.
       0.422
Your Current Organism:
Thermoproteus uzoniensis
NCBI taxonomy Id: 999630
Other names: T. uzoniensis 768-20, Thermoproteus uzoniensis 768-20, Thermoproteus uzoniensis str. 768-20, Thermoproteus uzoniensis strain 768-20
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