STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TDIS_1088Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2. (230 aa)    
Predicted Functional Partners:
TDIS_0632
Cysteine desulfurase.
   
 0.999
TDIS_1089
moaD family protein.
 
 0.991
TDIS_1090
Tungsten-containing aldehyde:ferredoxin oxidoreductase.
 
     0.835
nhaA
Na+/H+ antiporter NhaA type; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
       0.773
TDIS_0230
Phosphomethylpyrimidine kinase.
  
  
 0.741
TDIS_1811
Molybdopterin biosynthesis protein MoeA; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.
 
  
 0.687
thiC
Hydroxymethylpyrimidine phosphate synthase ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family.
  
  
 0.680
TDIS_1712
Thiamin biosynthesis protein ThiC.
  
  
 0.680
moaA
Molybdenum cofactor biosynthesis protein MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.
 
  
 0.645
moaC
Molybdenum cofactor biosynthesis protein MoaC; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family.
 
   
 0.644
Your Current Organism:
Thermosulfurimonas dismutans
NCBI taxonomy Id: 999894
Other names: DSM 24515, T. dismutans, Thermodesulfobacteriaceae bacterium S95, Thermosulfurimonas dismutans Slobodkin et al. 2012, VKM B-2683, strain S95
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