upp protein (Peptococcaceae bacterium CEB3) - STRING interaction network

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upp

Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (209 aa)

Predicted Functional Partners:

rpiB

0.964

udk

0.963

pyrH

0.961

guaA

0.960

glyA

0.954

pdp

0.908

sfrB_2

0.884

pyrF

0.877

tadA_2

0.869

pyrE

0.850

Your Current Organism:

Peptococcaceae bacterium CEB3

NCBI taxonomy Id: 999898
Other names: P. bacterium CEB3

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
glyA	guaA	CEB3_c41940	CEB3_c34990	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	GMP synthase; Catalyzes the synthesis of GMP from XMP.	0.910
glyA	pdp	CEB3_c41940	CEB3_c36880	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	Pyrimidine-nucleoside phosphorylase.	0.598
glyA	rpiB	CEB3_c41940	CEB3_c41920	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	Ribose-5-phosphate isomerase B.	0.986
glyA	sfrB_2	CEB3_c41940	CEB3_c31960	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	NADPH-Fe(3+) oxidoreductase subunit beta.	0.633
glyA	tadA_2	CEB3_c41940	CEB3_c41960	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	tRNA-specific adenosine deaminase.	0.808
glyA	upp	CEB3_c41940	CEB3_c41950	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.	0.954
guaA	glyA	CEB3_c34990	CEB3_c41940	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	0.910
guaA	pdp	CEB3_c34990	CEB3_c36880	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Pyrimidine-nucleoside phosphorylase.	0.687
guaA	pyrE	CEB3_c34990	CEB3_c33630	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).	0.943
guaA	pyrF	CEB3_c34990	CEB3_c33620	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.	0.786
guaA	pyrH	CEB3_c34990	CEB3_c03330	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.	0.851
guaA	rpiB	CEB3_c34990	CEB3_c41920	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Ribose-5-phosphate isomerase B.	0.505
guaA	sfrB_2	CEB3_c34990	CEB3_c31960	GMP synthase; Catalyzes the synthesis of GMP from XMP.	NADPH-Fe(3+) oxidoreductase subunit beta.	0.957
guaA	tadA_2	CEB3_c34990	CEB3_c41960	GMP synthase; Catalyzes the synthesis of GMP from XMP.	tRNA-specific adenosine deaminase.	0.476
guaA	udk	CEB3_c34990	CEB3_c34310	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Uridine kinase.	0.630
guaA	upp	CEB3_c34990	CEB3_c41950	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.	0.960
pdp	glyA	CEB3_c36880	CEB3_c41940	Pyrimidine-nucleoside phosphorylase.	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	0.598
pdp	guaA	CEB3_c36880	CEB3_c34990	Pyrimidine-nucleoside phosphorylase.	GMP synthase; Catalyzes the synthesis of GMP from XMP.	0.687
pdp	pyrE	CEB3_c36880	CEB3_c33630	Pyrimidine-nucleoside phosphorylase.	Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).	0.677
pdp	sfrB_2	CEB3_c36880	CEB3_c31960	Pyrimidine-nucleoside phosphorylase.	NADPH-Fe(3+) oxidoreductase subunit beta.	0.870