STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hemZOxygen-independent coproporphyrinogen-III oxidase-like protein HemZ. (683 aa)    
Predicted Functional Partners:
KLU58729.1
Putative metallo-hydrolase.
       0.837
hemN
Oxygen-independent coproporphyrinogen-III oxidase-like protein YqeR; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.
  
  
 
0.829
hemE_12
Uroporphyrinogen decarboxylase; Belongs to the uroporphyrinogen decarboxylase family.
  
 
 0.677
hemE_16
Uroporphyrinogen decarboxylase; Belongs to the uroporphyrinogen decarboxylase family.
  
 
 0.677
relA
GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
  
    0.660
dtd
D-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family.
       0.660
argS
arginine--tRNA ligase.
   
    0.653
KLU58642.1
Methylcobalamin:coenzyme M methyltransferase; Belongs to the uroporphyrinogen decarboxylase family.
  
 
 0.652
hemE_13
Uroporphyrinogen decarboxylase; Belongs to the uroporphyrinogen decarboxylase family.
  
 
 0.645
hemE_14
Uroporphyrinogen decarboxylase; Belongs to the uroporphyrinogen decarboxylase family.
  
 
 0.645
Your Current Organism:
Peptococcaceae bacterium CEB3
NCBI taxonomy Id: 999898
Other names: P. bacterium CEB3
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