STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MAP3K8Mitogen-activated protein kinase kinase kinase 8. (435 aa)    
Predicted Functional Partners:
NFKB1
Nuclear factor kappa B subunit 1.
   
 0.986
TNIP2
TNFAIP3 interacting protein 2.
   
 0.966
NFKB2
Nuclear factor kappa B subunit 2.
   
 0.954
MAP2K1
Mitogen-activated protein kinase kinase 1.
  
 
0.936
ENSUPAP00010011624
annotation not available
  
 
0.907
IKBKB
Inhibitor of nuclear factor kappa B kinase subunit beta.
    
0.882
CHUK
Component of inhibitor of nuclear factor kappa B kinase complex.
    
0.880
MAP3K14
Mitogen-activated protein kinase kinase kinase 14.
    
0.872
AKT1
AKT serine/threonine kinase 1.
   
 
0.868
MAP2K4
Mitogen-activated protein kinase kinase 4.
    
 
0.863
Your Current Organism:
Urocitellus parryii
NCBI taxonomy Id: 9999
Other names: Arctic ground squirrel, Citellus parryii, Spermophilus parryi, Spermophilus parryii, U. parryii
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.