PRKAA1 protein (Urocitellus parryii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

PRKAA1

Protein kinase AMP-activated catalytic subunit alpha 1. (559 aa)

Predicted Functional Partners:

PRKAB2

0.999

PRKAB1

0.999

PRKAG1

0.996

PRKAG2

0.995

PRKAG3

0.993

KMT2C

0.987

PRKAA2

0.967

STK11

0.958

TSC2

0.946

MAP3K7

0.935

Your Current Organism:

Urocitellus parryii

NCBI taxonomy Id: 9999
Other names: Arctic ground squirrel, Citellus parryii, Spermophilus parryi, Spermophilus parryii, U. parryii

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
KMT2C	MAP3K7	ENSUPAP00010014932	ENSUPAP00010024272	Lysine methyltransferase 2C.	Mitogen-activated protein kinase kinase kinase 7.	0.740
KMT2C	PRKAA1	ENSUPAP00010014932	ENSUPAP00010008054	Lysine methyltransferase 2C.	Protein kinase AMP-activated catalytic subunit alpha 1.	0.987
KMT2C	PRKAA2	ENSUPAP00010014932	ENSUPAP00010026582	Lysine methyltransferase 2C.	Protein kinase AMP-activated catalytic subunit alpha 2.	0.968
KMT2C	PRKAB1	ENSUPAP00010014932	ENSUPAP00010021930	Lysine methyltransferase 2C.	Protein kinase AMP-activated non-catalytic subunit beta 1.	0.994
KMT2C	PRKAB2	ENSUPAP00010014932	ENSUPAP00010018354	Lysine methyltransferase 2C.	Protein kinase AMP-activated non-catalytic subunit beta 2.	0.976
KMT2C	PRKAG1	ENSUPAP00010014932	ENSUPAP00010011498	Lysine methyltransferase 2C.	Protein kinase AMP-activated non-catalytic subunit gamma 1.	0.794
KMT2C	PRKAG2	ENSUPAP00010014932	ENSUPAP00010015070	Lysine methyltransferase 2C.	Protein kinase AMP-activated non-catalytic subunit gamma 2.	0.794
KMT2C	PRKAG3	ENSUPAP00010014932	ENSUPAP00010015572	Lysine methyltransferase 2C.	Protein kinase AMP-activated non-catalytic subunit gamma 3.	0.824
KMT2C	STK11	ENSUPAP00010014932	ENSUPAP00010017152	Lysine methyltransferase 2C.	Serine/threonine kinase 11.	0.862
MAP3K7	KMT2C	ENSUPAP00010024272	ENSUPAP00010014932	Mitogen-activated protein kinase kinase kinase 7.	Lysine methyltransferase 2C.	0.740
MAP3K7	PRKAA1	ENSUPAP00010024272	ENSUPAP00010008054	Mitogen-activated protein kinase kinase kinase 7.	Protein kinase AMP-activated catalytic subunit alpha 1.	0.935
MAP3K7	PRKAA2	ENSUPAP00010024272	ENSUPAP00010026582	Mitogen-activated protein kinase kinase kinase 7.	Protein kinase AMP-activated catalytic subunit alpha 2.	0.901
MAP3K7	PRKAB1	ENSUPAP00010024272	ENSUPAP00010021930	Mitogen-activated protein kinase kinase kinase 7.	Protein kinase AMP-activated non-catalytic subunit beta 1.	0.865
MAP3K7	PRKAB2	ENSUPAP00010024272	ENSUPAP00010018354	Mitogen-activated protein kinase kinase kinase 7.	Protein kinase AMP-activated non-catalytic subunit beta 2.	0.857
MAP3K7	PRKAG1	ENSUPAP00010024272	ENSUPAP00010011498	Mitogen-activated protein kinase kinase kinase 7.	Protein kinase AMP-activated non-catalytic subunit gamma 1.	0.852
MAP3K7	PRKAG2	ENSUPAP00010024272	ENSUPAP00010015070	Mitogen-activated protein kinase kinase kinase 7.	Protein kinase AMP-activated non-catalytic subunit gamma 2.	0.852
MAP3K7	PRKAG3	ENSUPAP00010024272	ENSUPAP00010015572	Mitogen-activated protein kinase kinase kinase 7.	Protein kinase AMP-activated non-catalytic subunit gamma 3.	0.862
MAP3K7	TSC2	ENSUPAP00010024272	ENSUPAP00010022001	Mitogen-activated protein kinase kinase kinase 7.	TSC complex subunit 2.	0.508
PRKAA1	KMT2C	ENSUPAP00010008054	ENSUPAP00010014932	Protein kinase AMP-activated catalytic subunit alpha 1.	Lysine methyltransferase 2C.	0.987
PRKAA1	MAP3K7	ENSUPAP00010008054	ENSUPAP00010024272	Protein kinase AMP-activated catalytic subunit alpha 1.	Mitogen-activated protein kinase kinase kinase 7.	0.935