STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DYRK4Dual specificity tyrosine phosphorylation regulated kinase 4. (487 aa)    
Predicted Functional Partners:
DCAF7
DDB1 and CUL4 associated factor 7.
   
 
 0.848
TP53
Tumor protein p53.
    
 0.789
ATM
ATM serine/threonine kinase.
    
 0.691
MDM4
MDM4 regulator of p53.
    
 0.690
PIN1
Peptidylprolyl cis/trans isomerase, NIMA-interacting 1.
    
 0.679
PLK2
Polo like kinase 2.
    
 
0.670
PLK1
Polo like kinase 1.
    
 
0.670
Plk5
Polo like kinase 5.
    
 
0.670
PLK3
Polo like kinase 3.
    
 
0.670
PLK4
Polo like kinase 4.
    
 
0.659
Your Current Organism:
Urocitellus parryii
NCBI taxonomy Id: 9999
Other names: Arctic ground squirrel, Citellus parryii, Spermophilus parryi, Spermophilus parryii, U. parryii
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.