node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BCAM | CD151 | ENSP00000270233 | ENSP00000324101 | Basal cell adhesion molecule; Laminin alpha-5 receptor. May mediate intracellular signaling. | CD151 antigen; Essential for the proper assembly of the glomerular and tubular basement membranes in kidney. | 0.485 |
BCAM | CNTN6 | ENSP00000270233 | ENSP00000407822 | Basal cell adhesion molecule; Laminin alpha-5 receptor. May mediate intracellular signaling. | Contactin-6; Contactins mediate cell surface interactions during nervous system development. Participates in oligodendrocytes generation by acting as a ligand of NOTCH1. Its association with NOTCH1 promotes NOTCH1 activation through the released notch intracellular domain (NICD) and subsequent translocation to the nucleus. Involved in motor coordination (By similarity); Belongs to the immunoglobulin superfamily. Contactin family. | 0.792 |
BCAM | FUT2 | ENSP00000270233 | ENSP00000387498 | Basal cell adhesion molecule; Laminin alpha-5 receptor. May mediate intracellular signaling. | Galactoside 2-alpha-L-fucosyltransferase 2; Mediates the transfer of fucose to the terminal galactose on glycan chains of cell surface glycoproteins and glycolipids. The resulting epitope plays a role in cell-cell interaction including host-microbe interaction. Mediates interaction with intestinal microbiota influencing its composition. Creates a soluble precursor oligosaccharide FuC-alpha ((1,2)Galbeta-) called the H antigen which is an essential substrate for the final step in the soluble ABO blood group antigen synthesis pathway. | 0.495 |
BCAM | ICAM4 | ENSP00000270233 | ENSP00000342114 | Basal cell adhesion molecule; Laminin alpha-5 receptor. May mediate intracellular signaling. | Intercellular adhesion molecule 4; ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). ICAM4 is also a ligand for alpha- 4/beta-1 and alpha-V integrins. | 0.581 |
BCAM | KEL | ENSP00000270233 | ENSP00000347409 | Basal cell adhesion molecule; Laminin alpha-5 receptor. May mediate intracellular signaling. | Kell blood group glycoprotein; Zinc endopeptidase with endothelin-3-converting enzyme activity. Cleaves EDN1, EDN2 and EDN3, with a marked preference for EDN3. | 0.552 |
BCAM | KLHL2 | ENSP00000270233 | ENSP00000424198 | Basal cell adhesion molecule; Laminin alpha-5 receptor. May mediate intracellular signaling. | Kelch-like protein 2; Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex that mediates the ubiquitination of target proteins, such as NPTXR, leading most often to their proteasomal degradation (By similarity). Responsible for degradative ubiquitination of the WNK kinases WNK1, WNK3 and WNK4. Plays a role in the reorganization of the actin cytoskeleton. Promotes growth of cell projections in oligodendrocyte precursors. | 0.625 |
BCAM | LAMA5 | ENSP00000270233 | ENSP00000252999 | Basal cell adhesion molecule; Laminin alpha-5 receptor. May mediate intracellular signaling. | Laminin subunit alpha-5; Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. | 0.946 |
BCAM | PDZD4 | ENSP00000270233 | ENSP00000377355 | Basal cell adhesion molecule; Laminin alpha-5 receptor. May mediate intracellular signaling. | PDZ domain containing 4. | 0.749 |
BCAM | UBE2I | ENSP00000270233 | ENSP00000348056 | Basal cell adhesion molecule; Laminin alpha-5 receptor. May mediate intracellular signaling. | SUMO-conjugating enzyme UBC9; Accepts the ubiquitin-like proteins SUMO1, SUMO2, SUMO3, SUMO4 and SUMO1P1/SUMO5 from the UBLE1A-UBLE1B E1 complex and catalyzes their covalent attachment to other proteins with the help of an E3 ligase such as RANBP2, CBX4 and ZNF451. Can catalyze the formation of poly-SUMO chains. Necessary for sumoylation of FOXL2 and KAT5. Essential for nuclear architecture and chromosome segregation. Sumoylates p53/TP53 at 'Lys-386'. Mediates sumoylation of ERCC6 which is essential for its transcription-coupled nucleotide excision repair activity. Belongs to the ubiqu [...] | 0.548 |
BCAM | ZSWIM2 | ENSP00000270233 | ENSP00000295131 | Basal cell adhesion molecule; Laminin alpha-5 receptor. May mediate intracellular signaling. | E3 ubiquitin-protein ligase ZSWIM2; E3 ubiquitin-protein ligase involved in the regulation of Fas-, DR3- and DR4-mediated apoptosis. Functions in conjunction with the UBE2D1, UBE2D3 and UBE2E1 E2 ubiquitin-conjugating enzymes. | 0.525 |
CD151 | BCAM | ENSP00000324101 | ENSP00000270233 | CD151 antigen; Essential for the proper assembly of the glomerular and tubular basement membranes in kidney. | Basal cell adhesion molecule; Laminin alpha-5 receptor. May mediate intracellular signaling. | 0.485 |
CNTN6 | BCAM | ENSP00000407822 | ENSP00000270233 | Contactin-6; Contactins mediate cell surface interactions during nervous system development. Participates in oligodendrocytes generation by acting as a ligand of NOTCH1. Its association with NOTCH1 promotes NOTCH1 activation through the released notch intracellular domain (NICD) and subsequent translocation to the nucleus. Involved in motor coordination (By similarity); Belongs to the immunoglobulin superfamily. Contactin family. | Basal cell adhesion molecule; Laminin alpha-5 receptor. May mediate intracellular signaling. | 0.792 |
CNTN6 | PDZD4 | ENSP00000407822 | ENSP00000377355 | Contactin-6; Contactins mediate cell surface interactions during nervous system development. Participates in oligodendrocytes generation by acting as a ligand of NOTCH1. Its association with NOTCH1 promotes NOTCH1 activation through the released notch intracellular domain (NICD) and subsequent translocation to the nucleus. Involved in motor coordination (By similarity); Belongs to the immunoglobulin superfamily. Contactin family. | PDZ domain containing 4. | 0.569 |
FUT2 | BCAM | ENSP00000387498 | ENSP00000270233 | Galactoside 2-alpha-L-fucosyltransferase 2; Mediates the transfer of fucose to the terminal galactose on glycan chains of cell surface glycoproteins and glycolipids. The resulting epitope plays a role in cell-cell interaction including host-microbe interaction. Mediates interaction with intestinal microbiota influencing its composition. Creates a soluble precursor oligosaccharide FuC-alpha ((1,2)Galbeta-) called the H antigen which is an essential substrate for the final step in the soluble ABO blood group antigen synthesis pathway. | Basal cell adhesion molecule; Laminin alpha-5 receptor. May mediate intracellular signaling. | 0.495 |
FUT2 | KEL | ENSP00000387498 | ENSP00000347409 | Galactoside 2-alpha-L-fucosyltransferase 2; Mediates the transfer of fucose to the terminal galactose on glycan chains of cell surface glycoproteins and glycolipids. The resulting epitope plays a role in cell-cell interaction including host-microbe interaction. Mediates interaction with intestinal microbiota influencing its composition. Creates a soluble precursor oligosaccharide FuC-alpha ((1,2)Galbeta-) called the H antigen which is an essential substrate for the final step in the soluble ABO blood group antigen synthesis pathway. | Kell blood group glycoprotein; Zinc endopeptidase with endothelin-3-converting enzyme activity. Cleaves EDN1, EDN2 and EDN3, with a marked preference for EDN3. | 0.555 |
FUT2 | PDZD4 | ENSP00000387498 | ENSP00000377355 | Galactoside 2-alpha-L-fucosyltransferase 2; Mediates the transfer of fucose to the terminal galactose on glycan chains of cell surface glycoproteins and glycolipids. The resulting epitope plays a role in cell-cell interaction including host-microbe interaction. Mediates interaction with intestinal microbiota influencing its composition. Creates a soluble precursor oligosaccharide FuC-alpha ((1,2)Galbeta-) called the H antigen which is an essential substrate for the final step in the soluble ABO blood group antigen synthesis pathway. | PDZ domain containing 4. | 0.505 |
ICAM4 | BCAM | ENSP00000342114 | ENSP00000270233 | Intercellular adhesion molecule 4; ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). ICAM4 is also a ligand for alpha- 4/beta-1 and alpha-V integrins. | Basal cell adhesion molecule; Laminin alpha-5 receptor. May mediate intracellular signaling. | 0.581 |
ICAM4 | KEL | ENSP00000342114 | ENSP00000347409 | Intercellular adhesion molecule 4; ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). ICAM4 is also a ligand for alpha- 4/beta-1 and alpha-V integrins. | Kell blood group glycoprotein; Zinc endopeptidase with endothelin-3-converting enzyme activity. Cleaves EDN1, EDN2 and EDN3, with a marked preference for EDN3. | 0.492 |
KEL | BCAM | ENSP00000347409 | ENSP00000270233 | Kell blood group glycoprotein; Zinc endopeptidase with endothelin-3-converting enzyme activity. Cleaves EDN1, EDN2 and EDN3, with a marked preference for EDN3. | Basal cell adhesion molecule; Laminin alpha-5 receptor. May mediate intracellular signaling. | 0.552 |
KEL | FUT2 | ENSP00000347409 | ENSP00000387498 | Kell blood group glycoprotein; Zinc endopeptidase with endothelin-3-converting enzyme activity. Cleaves EDN1, EDN2 and EDN3, with a marked preference for EDN3. | Galactoside 2-alpha-L-fucosyltransferase 2; Mediates the transfer of fucose to the terminal galactose on glycan chains of cell surface glycoproteins and glycolipids. The resulting epitope plays a role in cell-cell interaction including host-microbe interaction. Mediates interaction with intestinal microbiota influencing its composition. Creates a soluble precursor oligosaccharide FuC-alpha ((1,2)Galbeta-) called the H antigen which is an essential substrate for the final step in the soluble ABO blood group antigen synthesis pathway. | 0.555 |