STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C11orf87Uncharacterized protein C11orf87; Chromosome 11 open reading frame 87. (197 aa)    
Predicted Functional Partners:
OR5W2
Olfactory receptor 5W2; Odorant receptor; Belongs to the G-protein coupled receptor 1 family.
      
 0.507
CCT8L2
T-complex protein 1 subunit theta-like 2; Possible molecular chaperone; assists the folding of proteins upon ATP hydrolysis; Belongs to the TCP-1 chaperonin family.
      
 0.479
C11orf53
Uncharacterized protein C11orf53; Chromosome 11 open reading frame 53.
      
 0.479
COLCA2
Colorectal cancer associated 2.
      
 0.468
TMEM17
Transmembrane protein 17; Transmembrane component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Required for ciliogenesis and sonic hedgehog/SHH signaling (By similarity); Belongs to the TMEM17 family.
      
 0.461
TMEM87A
Transmembrane protein 87A; May be involved in retrograde transport from endosomes to the trans-Golgi network (TGN).
      
 0.448
C11orf88
UPF0722 protein C11orf88.
      
 0.430
ARHGAP20
Rho GTPase-activating protein 20; GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state.
   
  
 0.404
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.