STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CD164L2CD164 molecule like 2; Belongs to the CD164 family. (174 aa)    
Predicted Functional Partners:
TEKT3
Tektin-3; May be a structural component of the sperm flagellum. Required for normal sperm mobility.
      
 0.646
SLC19A1
Reduced folate transporter; Transporter that mediates the import of reduced folates and a subset of cyclic dinucleotides. Has high affinity for N5-methyltetrahydrofolate, the predominant circulating form of folate. Also able to mediate the import of antifolate drug methotrexate. Acts as an importer of immunoreactive cyclic dinucleotides, such as cyclic GMP-AMP (2'-3'-cGAMP), an immune messenger produced in response to DNA virus in the cytosol, and its linkage isomer 3'-3'-cGAMP. Mechanistically, acts as an antiporter, which export of intracellular organic anions to facilitate uptake of [...]
    
   0.628
CCER2
Coiled-coil glutamate rich protein 2.
      
 0.542
DCTN5
Dynactin subunit 5; Belongs to the dynactin subunits 5/6 family. Dynactin subunit 5 subfamily.
      
 0.507
ADGRF3
Adhesion G-protein coupled receptor F3; Orphan receptor.
      
 0.501
EMID1
EMI domain containing 1.
      
 0.446
RPRD2
Regulation of nuclear pre-mRNA domain containing 2.
      
 0.429
CLEC12B
C-type lectin domain family 12 member B; Cell surface receptor that protects target cells against natural killer cell-mediated lysis. Modulates signaling cascades and mediates tyrosine phosphorylation of target MAP kinases.
      
 0.426
ACBD7
Acyl-CoA-binding domain-containing protein 7; Binds medium- and long-chain acyl-CoA esters.
      
 0.424
LETMD1
LETM1 domain-containing protein 1; Involved in tumorigenesis and may function as a negative regulator of the p53/TP53.
    
   0.420
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.