node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
C2orf78 | CDKL4 | ENSP00000387124 | ENSP00000378476 | Uncharacterized protein C2orf78; Chromosome 2 open reading frame 78. | Cyclin-dependent kinase-like 4; Cyclin dependent kinase like 4. | 0.445 |
CDKL1 | CDKL4 | ENSP00000379176 | ENSP00000378476 | Cyclin-dependent kinase-like 1; Cyclin dependent kinase like 1; Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily. | Cyclin-dependent kinase-like 4; Cyclin dependent kinase like 4. | 0.791 |
CDKL1 | CTXN1 | ENSP00000379176 | ENSP00000313226 | Cyclin-dependent kinase-like 1; Cyclin dependent kinase like 1; Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily. | Cortexin-1; May mediate extracellular or intracellular signaling of cortical neurons during forebrain development; Belongs to the cortexin family. | 0.461 |
CDKL1 | DNAAF1 | ENSP00000379176 | ENSP00000367815 | Cyclin-dependent kinase-like 1; Cyclin dependent kinase like 1; Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily. | Dynein assembly factor 1, axonemal; Cilium-specific protein required for the stability of the ciliary architecture. Plays a role in cytoplasmic preassembly of dynein arms. Involved in regulation of microtubule-based cilia and actin-based brush border microvilli. | 0.472 |
CDKL1 | FKBP5 | ENSP00000379176 | ENSP00000444810 | Cyclin-dependent kinase-like 1; Cyclin dependent kinase like 1; Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily. | Peptidyl-prolyl cis-trans isomerase FKBP5; Immunophilin protein with PPIase and co-chaperone activities. Component of unligated steroid receptors heterocomplexes through interaction with heat-shock protein 90 (HSP90). Plays a role in the intracellular trafficking of heterooligomeric forms of steroid hormone receptors maintaining the complex into the cytoplasm when unliganded. Acts as a regulator of Akt/AKT1 activity by promoting the interaction between Akt/AKT1 and PHLPP1, thereby enhancing dephosphorylation and subsequent activation of Akt/AKT1. | 0.605 |
CDKL4 | C2orf78 | ENSP00000378476 | ENSP00000387124 | Cyclin-dependent kinase-like 4; Cyclin dependent kinase like 4. | Uncharacterized protein C2orf78; Chromosome 2 open reading frame 78. | 0.445 |
CDKL4 | CDKL1 | ENSP00000378476 | ENSP00000379176 | Cyclin-dependent kinase-like 4; Cyclin dependent kinase like 4. | Cyclin-dependent kinase-like 1; Cyclin dependent kinase like 1; Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily. | 0.791 |
CDKL4 | CTXN1 | ENSP00000378476 | ENSP00000313226 | Cyclin-dependent kinase-like 4; Cyclin dependent kinase like 4. | Cortexin-1; May mediate extracellular or intracellular signaling of cortical neurons during forebrain development; Belongs to the cortexin family. | 0.461 |
CDKL4 | DNAAF1 | ENSP00000378476 | ENSP00000367815 | Cyclin-dependent kinase-like 4; Cyclin dependent kinase like 4. | Dynein assembly factor 1, axonemal; Cilium-specific protein required for the stability of the ciliary architecture. Plays a role in cytoplasmic preassembly of dynein arms. Involved in regulation of microtubule-based cilia and actin-based brush border microvilli. | 0.461 |
CDKL4 | FKBP5 | ENSP00000378476 | ENSP00000444810 | Cyclin-dependent kinase-like 4; Cyclin dependent kinase like 4. | Peptidyl-prolyl cis-trans isomerase FKBP5; Immunophilin protein with PPIase and co-chaperone activities. Component of unligated steroid receptors heterocomplexes through interaction with heat-shock protein 90 (HSP90). Plays a role in the intracellular trafficking of heterooligomeric forms of steroid hormone receptors maintaining the complex into the cytoplasm when unliganded. Acts as a regulator of Akt/AKT1 activity by promoting the interaction between Akt/AKT1 and PHLPP1, thereby enhancing dephosphorylation and subsequent activation of Akt/AKT1. | 0.550 |
CDKL4 | GPATCH11 | ENSP00000378476 | ENSP00000386772 | Cyclin-dependent kinase-like 4; Cyclin dependent kinase like 4. | G-patch domain containing 11. | 0.435 |
CTXN1 | CDKL1 | ENSP00000313226 | ENSP00000379176 | Cortexin-1; May mediate extracellular or intracellular signaling of cortical neurons during forebrain development; Belongs to the cortexin family. | Cyclin-dependent kinase-like 1; Cyclin dependent kinase like 1; Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily. | 0.461 |
CTXN1 | CDKL4 | ENSP00000313226 | ENSP00000378476 | Cortexin-1; May mediate extracellular or intracellular signaling of cortical neurons during forebrain development; Belongs to the cortexin family. | Cyclin-dependent kinase-like 4; Cyclin dependent kinase like 4. | 0.461 |
DNAAF1 | CDKL1 | ENSP00000367815 | ENSP00000379176 | Dynein assembly factor 1, axonemal; Cilium-specific protein required for the stability of the ciliary architecture. Plays a role in cytoplasmic preassembly of dynein arms. Involved in regulation of microtubule-based cilia and actin-based brush border microvilli. | Cyclin-dependent kinase-like 1; Cyclin dependent kinase like 1; Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily. | 0.472 |
DNAAF1 | CDKL4 | ENSP00000367815 | ENSP00000378476 | Dynein assembly factor 1, axonemal; Cilium-specific protein required for the stability of the ciliary architecture. Plays a role in cytoplasmic preassembly of dynein arms. Involved in regulation of microtubule-based cilia and actin-based brush border microvilli. | Cyclin-dependent kinase-like 4; Cyclin dependent kinase like 4. | 0.461 |
FKBP5 | CDKL1 | ENSP00000444810 | ENSP00000379176 | Peptidyl-prolyl cis-trans isomerase FKBP5; Immunophilin protein with PPIase and co-chaperone activities. Component of unligated steroid receptors heterocomplexes through interaction with heat-shock protein 90 (HSP90). Plays a role in the intracellular trafficking of heterooligomeric forms of steroid hormone receptors maintaining the complex into the cytoplasm when unliganded. Acts as a regulator of Akt/AKT1 activity by promoting the interaction between Akt/AKT1 and PHLPP1, thereby enhancing dephosphorylation and subsequent activation of Akt/AKT1. | Cyclin-dependent kinase-like 1; Cyclin dependent kinase like 1; Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily. | 0.605 |
FKBP5 | CDKL4 | ENSP00000444810 | ENSP00000378476 | Peptidyl-prolyl cis-trans isomerase FKBP5; Immunophilin protein with PPIase and co-chaperone activities. Component of unligated steroid receptors heterocomplexes through interaction with heat-shock protein 90 (HSP90). Plays a role in the intracellular trafficking of heterooligomeric forms of steroid hormone receptors maintaining the complex into the cytoplasm when unliganded. Acts as a regulator of Akt/AKT1 activity by promoting the interaction between Akt/AKT1 and PHLPP1, thereby enhancing dephosphorylation and subsequent activation of Akt/AKT1. | Cyclin-dependent kinase-like 4; Cyclin dependent kinase like 4. | 0.550 |
GPATCH11 | CDKL4 | ENSP00000386772 | ENSP00000378476 | G-patch domain containing 11. | Cyclin-dependent kinase-like 4; Cyclin dependent kinase like 4. | 0.435 |