node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CRISP1 | CRISPLD2 | ENSP00000338276 | ENSP00000262424 | Cysteine-rich secretory protein 1; May have a role in sperm-egg fusion and maturation; Belongs to the CRISP family. | Cysteine-rich secretory protein LCCL domain-containing 2; Promotes matrix assembly; Belongs to the CRISP family. | 0.457 |
CRISP1 | GART | ENSP00000338276 | ENSP00000371253 | Cysteine-rich secretory protein 1; May have a role in sperm-egg fusion and maturation; Belongs to the CRISP family. | Trifunctional purine biosynthetic protein adenosine-3; Phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase; In the central section; belongs to the AIR synthase family. | 0.831 |
CRISP1 | GLIPR2 | ENSP00000338276 | ENSP00000367196 | Cysteine-rich secretory protein 1; May have a role in sperm-egg fusion and maturation; Belongs to the CRISP family. | Golgi-associated plant pathogenesis-related protein 1; GLI pathogenesis related 2. | 0.527 |
CRISP2 | CRISP3 | ENSP00000484609 | ENSP00000389026 | Cysteine-rich secretory protein 2; May regulate some ion channels' activity and therebye regulate calcium fluxes during sperm capacitation. | Cysteine rich secretory protein 3; Belongs to the CRISP family. | 0.666 |
CRISP2 | CRISPLD2 | ENSP00000484609 | ENSP00000262424 | Cysteine-rich secretory protein 2; May regulate some ion channels' activity and therebye regulate calcium fluxes during sperm capacitation. | Cysteine-rich secretory protein LCCL domain-containing 2; Promotes matrix assembly; Belongs to the CRISP family. | 0.437 |
CRISP2 | GART | ENSP00000484609 | ENSP00000371253 | Cysteine-rich secretory protein 2; May regulate some ion channels' activity and therebye regulate calcium fluxes during sperm capacitation. | Trifunctional purine biosynthetic protein adenosine-3; Phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase; In the central section; belongs to the AIR synthase family. | 0.831 |
CRISP3 | CRISP2 | ENSP00000389026 | ENSP00000484609 | Cysteine rich secretory protein 3; Belongs to the CRISP family. | Cysteine-rich secretory protein 2; May regulate some ion channels' activity and therebye regulate calcium fluxes during sperm capacitation. | 0.666 |
CRISP3 | CRISPLD2 | ENSP00000389026 | ENSP00000262424 | Cysteine rich secretory protein 3; Belongs to the CRISP family. | Cysteine-rich secretory protein LCCL domain-containing 2; Promotes matrix assembly; Belongs to the CRISP family. | 0.436 |
CRISP3 | GART | ENSP00000389026 | ENSP00000371253 | Cysteine rich secretory protein 3; Belongs to the CRISP family. | Trifunctional purine biosynthetic protein adenosine-3; Phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase; In the central section; belongs to the AIR synthase family. | 0.831 |
CRISPLD2 | CRISP1 | ENSP00000262424 | ENSP00000338276 | Cysteine-rich secretory protein LCCL domain-containing 2; Promotes matrix assembly; Belongs to the CRISP family. | Cysteine-rich secretory protein 1; May have a role in sperm-egg fusion and maturation; Belongs to the CRISP family. | 0.457 |
CRISPLD2 | CRISP2 | ENSP00000262424 | ENSP00000484609 | Cysteine-rich secretory protein LCCL domain-containing 2; Promotes matrix assembly; Belongs to the CRISP family. | Cysteine-rich secretory protein 2; May regulate some ion channels' activity and therebye regulate calcium fluxes during sperm capacitation. | 0.437 |
CRISPLD2 | CRISP3 | ENSP00000262424 | ENSP00000389026 | Cysteine-rich secretory protein LCCL domain-containing 2; Promotes matrix assembly; Belongs to the CRISP family. | Cysteine rich secretory protein 3; Belongs to the CRISP family. | 0.436 |
CRISPLD2 | FOLR2 | ENSP00000262424 | ENSP00000298223 | Cysteine-rich secretory protein LCCL domain-containing 2; Promotes matrix assembly; Belongs to the CRISP family. | Folate receptor beta; Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. Has high affinity for folate and folic acid analogs at neutral pH. Exposure to slightly acidic pH after receptor endocytosis triggers a conformation change that strongly reduces its affinity for folates and mediates their release. | 0.414 |
CRISPLD2 | FOXE1 | ENSP00000262424 | ENSP00000364265 | Cysteine-rich secretory protein LCCL domain-containing 2; Promotes matrix assembly; Belongs to the CRISP family. | Forkhead box protein E1; Transcription factor that binds consensus sites on a variety of gene promoters and activate their transcription. Involved in proper palate formation, most probably through the expression of MSX1 and TGFB3 genes which are direct targets of this transcription factor. Also implicated in thyroid gland morphogenesis. May indirectly play a role in cell growth and migration through the regulation of WNT5A expression. | 0.466 |
CRISPLD2 | GART | ENSP00000262424 | ENSP00000371253 | Cysteine-rich secretory protein LCCL domain-containing 2; Promotes matrix assembly; Belongs to the CRISP family. | Trifunctional purine biosynthetic protein adenosine-3; Phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase; In the central section; belongs to the AIR synthase family. | 0.831 |
CRISPLD2 | GLIPR2 | ENSP00000262424 | ENSP00000367196 | Cysteine-rich secretory protein LCCL domain-containing 2; Promotes matrix assembly; Belongs to the CRISP family. | Golgi-associated plant pathogenesis-related protein 1; GLI pathogenesis related 2. | 0.458 |
CRISPLD2 | IRF6 | ENSP00000262424 | ENSP00000355988 | Cysteine-rich secretory protein LCCL domain-containing 2; Promotes matrix assembly; Belongs to the CRISP family. | Interferon regulatory factor 6; Probable DNA-binding transcriptional activator. Key determinant of the keratinocyte proliferation-differentiation switch involved in appropriate epidermal development (By similarity). Plays a role in regulating mammary epithelial cell proliferation (By similarity). May regulate WDR65 transcription (By similarity). Belongs to the IRF family. | 0.523 |
CRISPLD2 | MSX1 | ENSP00000262424 | ENSP00000372170 | Cysteine-rich secretory protein LCCL domain-containing 2; Promotes matrix assembly; Belongs to the CRISP family. | Homeobox protein MSX-1; Acts as a transcriptional repressor. May play a role in limb- pattern formation. Acts in cranofacial development and specifically in odontogenesis. Expression in the developing nail bed mesenchyme is important for nail plate thickness and integrity. Belongs to the Msh homeobox family. | 0.431 |
CRISPLD2 | TULP2 | ENSP00000262424 | ENSP00000221399 | Cysteine-rich secretory protein LCCL domain-containing 2; Promotes matrix assembly; Belongs to the CRISP family. | TUB like protein 2; Belongs to the TUB family. | 0.423 |
FOLR2 | CRISPLD2 | ENSP00000298223 | ENSP00000262424 | Folate receptor beta; Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. Has high affinity for folate and folic acid analogs at neutral pH. Exposure to slightly acidic pH after receptor endocytosis triggers a conformation change that strongly reduces its affinity for folates and mediates their release. | Cysteine-rich secretory protein LCCL domain-containing 2; Promotes matrix assembly; Belongs to the CRISP family. | 0.414 |