node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EDF1 | FAU | ENSP00000224073 | ENSP00000431822 | Endothelial differentiation-related factor 1; Transcriptional coactivator stimulating NR5A1 and ligand- dependent NR1H3/LXRA and PPARG transcriptional activities. Enhances the DNA-binding activity of ATF1, ATF2, CREB1 and NR5A1. Regulates nitric oxid synthase activity probably by sequestering calmodulin in the cytoplasm. May function in endothelial cells differentiation, hormone- induced cardiomyocytes hypertrophy and lipid metabolism. | Ubiquitin-like protein FUBI; FAU ubiquitin like and ribosomal protein S30 fusion. | 0.997 |
EDF1 | RACK1 | ENSP00000224073 | ENSP00000426909 | Endothelial differentiation-related factor 1; Transcriptional coactivator stimulating NR5A1 and ligand- dependent NR1H3/LXRA and PPARG transcriptional activities. Enhances the DNA-binding activity of ATF1, ATF2, CREB1 and NR5A1. Regulates nitric oxid synthase activity probably by sequestering calmodulin in the cytoplasm. May function in endothelial cells differentiation, hormone- induced cardiomyocytes hypertrophy and lipid metabolism. | Receptor of activated protein C kinase 1, N-terminally processed; Scaffolding protein involved in the recruitment, assembly and/or regulation of a variety of signaling molecules. Interacts with a wide variety of proteins and plays a role in many cellular processes. Component of the 40S ribosomal subunit involved in translational repression. Involved in the initiation of the ribosome quality control (RQC), a pathway that takes place when a ribosome has stalled during translation, by promoting ubiquitination of a subset of 40S ribosomal subunits. Binds to and stabilizes activated protein [...] | 0.977 |
EDF1 | RPS10 | ENSP00000224073 | ENSP00000481646 | Endothelial differentiation-related factor 1; Transcriptional coactivator stimulating NR5A1 and ligand- dependent NR1H3/LXRA and PPARG transcriptional activities. Enhances the DNA-binding activity of ATF1, ATF2, CREB1 and NR5A1. Regulates nitric oxid synthase activity probably by sequestering calmodulin in the cytoplasm. May function in endothelial cells differentiation, hormone- induced cardiomyocytes hypertrophy and lipid metabolism. | 40S ribosomal protein S10; Component of the 40S ribosomal subunit; Belongs to the eukaryotic ribosomal protein eS10 family. | 0.969 |
EDF1 | RPS15 | ENSP00000224073 | ENSP00000466010 | Endothelial differentiation-related factor 1; Transcriptional coactivator stimulating NR5A1 and ligand- dependent NR1H3/LXRA and PPARG transcriptional activities. Enhances the DNA-binding activity of ATF1, ATF2, CREB1 and NR5A1. Regulates nitric oxid synthase activity probably by sequestering calmodulin in the cytoplasm. May function in endothelial cells differentiation, hormone- induced cardiomyocytes hypertrophy and lipid metabolism. | Ribosomal protein S15. | 0.967 |
EDF1 | RPS2 | ENSP00000224073 | ENSP00000341885 | Endothelial differentiation-related factor 1; Transcriptional coactivator stimulating NR5A1 and ligand- dependent NR1H3/LXRA and PPARG transcriptional activities. Enhances the DNA-binding activity of ATF1, ATF2, CREB1 and NR5A1. Regulates nitric oxid synthase activity probably by sequestering calmodulin in the cytoplasm. May function in endothelial cells differentiation, hormone- induced cardiomyocytes hypertrophy and lipid metabolism. | Ribosomal protein S2. | 0.968 |
EDF1 | RPS20 | ENSP00000224073 | ENSP00000429374 | Endothelial differentiation-related factor 1; Transcriptional coactivator stimulating NR5A1 and ligand- dependent NR1H3/LXRA and PPARG transcriptional activities. Enhances the DNA-binding activity of ATF1, ATF2, CREB1 and NR5A1. Regulates nitric oxid synthase activity probably by sequestering calmodulin in the cytoplasm. May function in endothelial cells differentiation, hormone- induced cardiomyocytes hypertrophy and lipid metabolism. | Ribosomal protein S20. | 0.976 |
EDF1 | RPS21 | ENSP00000224073 | ENSP00000345957 | Endothelial differentiation-related factor 1; Transcriptional coactivator stimulating NR5A1 and ligand- dependent NR1H3/LXRA and PPARG transcriptional activities. Enhances the DNA-binding activity of ATF1, ATF2, CREB1 and NR5A1. Regulates nitric oxid synthase activity probably by sequestering calmodulin in the cytoplasm. May function in endothelial cells differentiation, hormone- induced cardiomyocytes hypertrophy and lipid metabolism. | Ribosomal protein S21; Belongs to the eukaryotic ribosomal protein eS21 family. | 0.962 |
EDF1 | RPS3 | ENSP00000224073 | ENSP00000278572 | Endothelial differentiation-related factor 1; Transcriptional coactivator stimulating NR5A1 and ligand- dependent NR1H3/LXRA and PPARG transcriptional activities. Enhances the DNA-binding activity of ATF1, ATF2, CREB1 and NR5A1. Regulates nitric oxid synthase activity probably by sequestering calmodulin in the cytoplasm. May function in endothelial cells differentiation, hormone- induced cardiomyocytes hypertrophy and lipid metabolism. | 40S ribosomal protein S3; Involved in translation as a component of the 40S small ribosomal subunit. Has endonuclease activity and plays a role in repair of damaged DNA. Cleaves phosphodiester bonds of DNAs containing altered bases with broad specificity and cleaves supercoiled DNA more efficiently than relaxed DNA. Displays high binding affinity for 7,8-dihydro- 8-oxoguanine (8-oxoG), a common DNA lesion caused by reactive oxygen species (ROS). Has also been shown to bind with similar affinity to intact and damaged DNA. Stimulates the N-glycosylase activity of the base excision protei [...] | 0.994 |
EDF1 | RPS5 | ENSP00000224073 | ENSP00000472985 | Endothelial differentiation-related factor 1; Transcriptional coactivator stimulating NR5A1 and ligand- dependent NR1H3/LXRA and PPARG transcriptional activities. Enhances the DNA-binding activity of ATF1, ATF2, CREB1 and NR5A1. Regulates nitric oxid synthase activity probably by sequestering calmodulin in the cytoplasm. May function in endothelial cells differentiation, hormone- induced cardiomyocytes hypertrophy and lipid metabolism. | 40S ribosomal protein S5, N-terminally processed; Ribosomal protein S5; Belongs to the universal ribosomal protein uS7 family. | 0.962 |
EDF1 | RPS9 | ENSP00000224073 | ENSP00000375632 | Endothelial differentiation-related factor 1; Transcriptional coactivator stimulating NR5A1 and ligand- dependent NR1H3/LXRA and PPARG transcriptional activities. Enhances the DNA-binding activity of ATF1, ATF2, CREB1 and NR5A1. Regulates nitric oxid synthase activity probably by sequestering calmodulin in the cytoplasm. May function in endothelial cells differentiation, hormone- induced cardiomyocytes hypertrophy and lipid metabolism. | Ribosomal protein S9. | 0.981 |
FAU | EDF1 | ENSP00000431822 | ENSP00000224073 | Ubiquitin-like protein FUBI; FAU ubiquitin like and ribosomal protein S30 fusion. | Endothelial differentiation-related factor 1; Transcriptional coactivator stimulating NR5A1 and ligand- dependent NR1H3/LXRA and PPARG transcriptional activities. Enhances the DNA-binding activity of ATF1, ATF2, CREB1 and NR5A1. Regulates nitric oxid synthase activity probably by sequestering calmodulin in the cytoplasm. May function in endothelial cells differentiation, hormone- induced cardiomyocytes hypertrophy and lipid metabolism. | 0.997 |
FAU | RACK1 | ENSP00000431822 | ENSP00000426909 | Ubiquitin-like protein FUBI; FAU ubiquitin like and ribosomal protein S30 fusion. | Receptor of activated protein C kinase 1, N-terminally processed; Scaffolding protein involved in the recruitment, assembly and/or regulation of a variety of signaling molecules. Interacts with a wide variety of proteins and plays a role in many cellular processes. Component of the 40S ribosomal subunit involved in translational repression. Involved in the initiation of the ribosome quality control (RQC), a pathway that takes place when a ribosome has stalled during translation, by promoting ubiquitination of a subset of 40S ribosomal subunits. Binds to and stabilizes activated protein [...] | 0.999 |
FAU | RPS10 | ENSP00000431822 | ENSP00000481646 | Ubiquitin-like protein FUBI; FAU ubiquitin like and ribosomal protein S30 fusion. | 40S ribosomal protein S10; Component of the 40S ribosomal subunit; Belongs to the eukaryotic ribosomal protein eS10 family. | 0.999 |
FAU | RPS15 | ENSP00000431822 | ENSP00000466010 | Ubiquitin-like protein FUBI; FAU ubiquitin like and ribosomal protein S30 fusion. | Ribosomal protein S15. | 0.999 |
FAU | RPS2 | ENSP00000431822 | ENSP00000341885 | Ubiquitin-like protein FUBI; FAU ubiquitin like and ribosomal protein S30 fusion. | Ribosomal protein S2. | 0.999 |
FAU | RPS20 | ENSP00000431822 | ENSP00000429374 | Ubiquitin-like protein FUBI; FAU ubiquitin like and ribosomal protein S30 fusion. | Ribosomal protein S20. | 0.999 |
FAU | RPS21 | ENSP00000431822 | ENSP00000345957 | Ubiquitin-like protein FUBI; FAU ubiquitin like and ribosomal protein S30 fusion. | Ribosomal protein S21; Belongs to the eukaryotic ribosomal protein eS21 family. | 0.999 |
FAU | RPS3 | ENSP00000431822 | ENSP00000278572 | Ubiquitin-like protein FUBI; FAU ubiquitin like and ribosomal protein S30 fusion. | 40S ribosomal protein S3; Involved in translation as a component of the 40S small ribosomal subunit. Has endonuclease activity and plays a role in repair of damaged DNA. Cleaves phosphodiester bonds of DNAs containing altered bases with broad specificity and cleaves supercoiled DNA more efficiently than relaxed DNA. Displays high binding affinity for 7,8-dihydro- 8-oxoguanine (8-oxoG), a common DNA lesion caused by reactive oxygen species (ROS). Has also been shown to bind with similar affinity to intact and damaged DNA. Stimulates the N-glycosylase activity of the base excision protei [...] | 0.999 |
FAU | RPS5 | ENSP00000431822 | ENSP00000472985 | Ubiquitin-like protein FUBI; FAU ubiquitin like and ribosomal protein S30 fusion. | 40S ribosomal protein S5, N-terminally processed; Ribosomal protein S5; Belongs to the universal ribosomal protein uS7 family. | 0.999 |
FAU | RPS9 | ENSP00000431822 | ENSP00000375632 | Ubiquitin-like protein FUBI; FAU ubiquitin like and ribosomal protein S30 fusion. | Ribosomal protein S9. | 0.999 |